A cholesterol-dependent switch controls organ-specific metastasis in pancreatic cancer

As different organs offer distinct chemical microenvironments, cancer cells require unique metabolic adaptation to colonize distant sites. In a recent issue of Nature, Rademaker et al. identify PCSK9 as a predictive factor for metastatic colonization of different organs, showing adaptation of cancer...

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Bibliographic Details
Main Authors: Haenlin, Julie (Author) , Schulze, Almut (Author)
Format: Article (Journal)
Language:English
Published: 4 August 2025
In: Developmental cell
Year: 2025, Volume: 60, Issue: 15, Pages: 2029-2031
ISSN:1878-1551
DOI:10.1016/j.devcel.2025.07.001
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.devcel.2025.07.001
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1534580725004393
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Author Notes:Julie Haenlin and Almut Schulze

MARC

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