Expression and functional evaluation of ABC and SLC transporters in Human Choroid Plexus Papilloma (HIBCPP) cells: a human blood-cerebrospinal fluid barrier model
Human choroid plexus papilloma (HIBCPP) cells derived from choroid plexus papilloma in the lateral ventricle are considered suitable model cells for the blood-cerebrospinal fluid barrier (BCSFB). Therefore, in this study, the transporters expressed in HIBCPP cells were identified, and the functions...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
10 December 2025
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| In: |
Pharmaceutical research
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| ISSN: | 1573-904X |
| DOI: | 10.1007/s11095-025-03987-0 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11095-025-03987-0
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| Verfasserangaben: | Toshiki Kurosawa, Sumio Ohtsuki, Hiroshi Ishikawa, Horst Schroten, Christian Schwerk, Yoshiyuki Kubo, Yoshiharu Deguchi |
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| 520 | |a Human choroid plexus papilloma (HIBCPP) cells derived from choroid plexus papilloma in the lateral ventricle are considered suitable model cells for the blood-cerebrospinal fluid barrier (BCSFB). Therefore, in this study, the transporters expressed in HIBCPP cells were identified, and the functions of representative transporters were evaluated. | ||
| 650 | 4 | |a ATP-binding cassette transporter | |
| 650 | 4 | |a blood-cerebrospinal fluid barrier | |
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| 650 | 4 | |a solute carrier transporter | |
| 650 | 4 | |a tight junction | |
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