MODOMICS: a database of RNA modifications and related information : 2025 update and 20th anniversary
MODOMICS is the reference database of RNA modifications and related information, integrating chemical, biochemical, structural, and functional data. In this 2025 update, marking the 20th anniversary of MODOMICS, the database has been significantly expanded in scope and depth. The RNA sequence sectio...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
24 November 2025
|
| In: |
Nucleic acids research
Year: 2025, Pages: 1-7 |
| ISSN: | 1362-4962 |
| DOI: | 10.1093/nar/gkaf1284 |
| Online Access: | Resolving-System, kostenfrei, Volltext: https://doi.org/10.1093/nar/gkaf1284 Verlag, kostenfrei, Volltext: https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaf1284/8340980 
|
| Author Notes: | Dominik Sordyl, Etienne Boileau, Agata Bernat, Satyabrata Maiti, Sunandan Mukherjee, S. Naeim Moafinejad, Masoud Amiri Farsani, Anastasiya Shavina, Andrea Cappannini, Giada Agostini, Silvestro G. Conticello, Filip Stefaniak, Christoph Dieterich, Elżbieta Purta, Janusz M. Bujnicki |
MARC
| LEADER | 00000naa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1948844524 | ||
| 003 | DE-627 | ||
| 005 | 20260114183051.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 260114s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1093/nar/gkaf1284 |2 doi | |
| 035 | |a (DE-627)1948844524 | ||
| 035 | |a (DE-599)KXP1948844524 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Sordyl, Dominik |e VerfasserIn |0 (DE-588)1386711403 |0 (DE-627)1948844583 |4 aut | |
| 245 | 1 | 0 | |a MODOMICS |b a database of RNA modifications and related information : 2025 update and 20th anniversary |c Dominik Sordyl, Etienne Boileau, Agata Bernat, Satyabrata Maiti, Sunandan Mukherjee, S. Naeim Moafinejad, Masoud Amiri Farsani, Anastasiya Shavina, Andrea Cappannini, Giada Agostini, Silvestro G. Conticello, Filip Stefaniak, Christoph Dieterich, Elżbieta Purta, Janusz M. Bujnicki |
| 264 | 1 | |c 24 November 2025 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 14.01.2026 | ||
| 520 | |a MODOMICS is the reference database of RNA modifications and related information, integrating chemical, biochemical, structural, and functional data. In this 2025 update, marking the 20th anniversary of MODOMICS, the database has been significantly expanded in scope and depth. The RNA sequence section now includes transcriptome-wide data generated in collaboration with Sci-ModoM, a quantitative resource of high-throughput epitranscriptomic datasets, enabling the representation of >48 000 transcripts with high-confidence modification annotations. The catalog of modified residues was improved with systematic curation, and addition of new computational descriptors derived from quantum mechanical calculations. An all-versus-all similarity analysis of chemical structures was performed, and the results are provided as an interactive similarity graph to explore chemical relationships among modifications. The protein section has been updated with newly characterized enzymes and expanded annotations of modification pathways, supported by an improved evidence and reliability framework. Together, these advances further strengthen MODOMICS as a comprehensive and reliable community resource, serving as both a reference and a platform for discovery in the rapidly developing field of epitranscriptomics. MODOMICS is available at https://iimcb.genesilico.pl/modomics/. | ||
| 700 | 1 | |a Boileau, Etienne |e VerfasserIn |0 (DE-588)1194473482 |0 (DE-627)1676464018 |4 aut | |
| 700 | 1 | |a Bernat, Agata |e VerfasserIn |4 aut | |
| 700 | 1 | |a Maiti, Satyabrata |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mukherjee, Sunandan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Moafinejad, S Naeim |e VerfasserIn |4 aut | |
| 700 | 1 | |a Farsani, Masoud Amiri |e VerfasserIn |4 aut | |
| 700 | 1 | |a Shavina, Anastasiya |e VerfasserIn |4 aut | |
| 700 | 1 | |a Cappannini, Andrea |e VerfasserIn |4 aut | |
| 700 | 1 | |a Agostini, Giada |e VerfasserIn |4 aut | |
| 700 | 1 | |a Conticello, Silvestro G |e VerfasserIn |4 aut | |
| 700 | 1 | |a Stefaniak, Filip |e VerfasserIn |4 aut | |
| 700 | 1 | |a Dieterich, Christoph |d 1975- |e VerfasserIn |0 (DE-588)130054844 |0 (DE-627)494359269 |0 (DE-576)297972448 |4 aut | |
| 700 | 1 | |a Purta, Elżbieta |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bujnicki, Janusz M. |d 1975- |e VerfasserIn |0 (DE-588)1156055644 |0 (DE-627)1018618856 |0 (DE-576)502012846 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nucleic acids research |d Oxford : Oxford Univ. Press, 1974 |g (2025), Artikel-ID gkaf1284, Seite 1-7 |h Online-Ressource |w (DE-627)26813250X |w (DE-600)1472175-2 |w (DE-576)07760878X |x 1362-4962 |7 nnas |a MODOMICS a database of RNA modifications and related information : 2025 update and 20th anniversary |
| 773 | 1 | 8 | |g year:2025 |g elocationid:gkaf1284 |g pages:1-7 |g extent:7 |a MODOMICS a database of RNA modifications and related information : 2025 update and 20th anniversary |
| 856 | 4 | 0 | |u https://doi.org/10.1093/nar/gkaf1284 |x Resolving-System |x Verlag |z kostenfrei |3 Volltext |7 0 |
| 856 | 4 | 0 | |u https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaf1284/8340980 |x Verlag |z kostenfrei |3 Volltext |7 0 |
| 951 | |a AR | ||
| 992 | |a 20260114 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 130054844 |a Dieterich, Christoph |m 130054844:Dieterich, Christoph |d 910000 |d 910100 |e 910000PD130054844 |e 910100PD130054844 |k 0/910000/ |k 1/910000/910100/ |p 13 | ||
| 998 | |g 1194473482 |a Boileau, Etienne |m 1194473482:Boileau, Etienne |d 910000 |d 910100 |e 910000PB1194473482 |e 910100PB1194473482 |k 0/910000/ |k 1/910000/910100/ |p 2 | ||
| 999 | |a KXP-PPN1948844524 |e 4848542405 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Dominik Sordyl, Etienne Boileau, Agata Bernat, Satyabrata Maiti, Sunandan Mukherjee, S. Naeim Moafinejad, Masoud Amiri Farsani, Anastasiya Shavina, Andrea Cappannini, Giada Agostini, Silvestro G. Conticello, Filip Stefaniak, Christoph Dieterich, Elżbieta Purta, Janusz M. Bujnicki"]},"id":{"eki":["1948844524"],"doi":["10.1093/nar/gkaf1284"]},"physDesc":[{"extent":"7 S."}],"recId":"1948844524","origin":[{"dateIssuedDisp":"24 November 2025","dateIssuedKey":"2025"}],"relHost":[{"pubHistory":["1.1974 -"],"titleAlt":[{"title":"NAR online"},{"title":"NAR"},{"title":"Database issue"},{"title":"Web server issue"}],"part":{"year":"2025","pages":"1-7","extent":"7","text":"(2025), Artikel-ID gkaf1284, Seite 1-7"},"id":{"zdb":["1472175-2"],"issn":["1362-4962"],"eki":["26813250X"]},"recId":"26813250X","physDesc":[{"extent":"Online-Ressource"}],"disp":"MODOMICS a database of RNA modifications and related information : 2025 update and 20th anniversaryNucleic acids research","origin":[{"publisher":"Oxford Univ. Press","publisherPlace":"Oxford","dateIssuedKey":"1974","dateIssuedDisp":"1974-"}],"title":[{"title_sort":"Nucleic acids research","title":"Nucleic acids research"}],"note":["Gesehen am 15.09.2025","Ungezählte Beil.: Database issue; Web server issue"],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"}}],"person":[{"display":"Sordyl, Dominik","family":"Sordyl","given":"Dominik","role":"aut"},{"display":"Boileau, Etienne","given":"Etienne","role":"aut","family":"Boileau"},{"display":"Bernat, Agata","given":"Agata","role":"aut","family":"Bernat"},{"display":"Maiti, Satyabrata","family":"Maiti","role":"aut","given":"Satyabrata"},{"display":"Mukherjee, Sunandan","given":"Sunandan","role":"aut","family":"Mukherjee"},{"display":"Moafinejad, S Naeim","role":"aut","given":"S Naeim","family":"Moafinejad"},{"role":"aut","given":"Masoud Amiri","family":"Farsani","display":"Farsani, Masoud Amiri"},{"given":"Anastasiya","role":"aut","family":"Shavina","display":"Shavina, Anastasiya"},{"display":"Cappannini, Andrea","family":"Cappannini","role":"aut","given":"Andrea"},{"display":"Agostini, Giada","family":"Agostini","role":"aut","given":"Giada"},{"display":"Conticello, Silvestro G","family":"Conticello","role":"aut","given":"Silvestro G"},{"display":"Stefaniak, Filip","family":"Stefaniak","role":"aut","given":"Filip"},{"family":"Dieterich","role":"aut","given":"Christoph","display":"Dieterich, Christoph"},{"display":"Purta, Elżbieta","role":"aut","given":"Elżbieta","family":"Purta"},{"display":"Bujnicki, Janusz M.","family":"Bujnicki","role":"aut","given":"Janusz M."}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"note":["Gesehen am 14.01.2026"],"title":[{"subtitle":"a database of RNA modifications and related information : 2025 update and 20th anniversary","title":"MODOMICS","title_sort":"MODOMICS"}]} | ||
| SRT | |a SORDYLDOMIMODOMICS2420 | ||