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Biphasic myoepithelial carcinoma with 5p/5q loss: morphomolecular characterization and provisional designation of a proposed novel salivary tumor entity

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Salivary gland tumors are diagnostically challenging due to major diversity of benign and malignant tumors with enormous intra-tumorous and inter-tumorous heterogeneity and, hence, frequently overlapping histologic features. DNA methylation has greatly enhanced tumor classification in several organs...

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Main Authors: Jurmeister, Philipp (Author) , Leitheiser, Maximilian (Author) , Bergmayr, Linda (Author) , Payá Capilla, Emma (Author) , Mochmann, Liliana H. (Author) , Zhdanovich, Yauheniya (Author) , Engelhardt-Schott, Fabian (Author) , Schleich, Konstanze (Author) , Klingler, Doreen (Author) , Chimal, Edgar (Author) , Focke, Cornelia M. (Author) , Breimer, Gerben E. (Author) , van Engen van Grunsven, Ilse (Author) , Deimling, Andreas von (Author) , Capper, David (Author) , Klauschen, Frederick (Author) , Ihrler, Stephan (Author)
Format: Article (Journal)
Language:English
Published: September 2025
In: The American journal of surgical pathology
Year: 2025, Volume: 49, Issue: 9, Pages: 890-900
ISSN:1532-0979
DOI:10.1097/PAS.0000000000002450
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/PAS.0000000000002450
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/ajsp/fulltext/2025/09010/biphasic_myoepithelial_carcinoma_with_5p_5q_loss_.4.aspx
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Author Notes:Philipp Jurmeister, MD, Maximilian Leitheiser, MSc, Linda Bergmayr, MSc, Emma Payá Capilla, BSc, Liliana H. Mochmann, PhD, Yauheniya Zhdanovich, MSc, Fabian Engelhardt-Schott, Konstanze Schleich, Doreen Klingler, MSc, Edgar Chimal, BSc, Cornelia M. Focke, MD, Gerben E. Breimer, MD, Ilse van Engen van Grunsven, MD, Andreas von Deimling, MD, David Capper, MD, Frederick Klauschen, MD, and Stephan Ihrler, MD
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FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma by Remke, Marc (Author) , Hielscher, Thomas (Author) , Korshunov, Andrey (Author) , Northcott, Paul A. (Author) , Bender, Sebastian (Author) , Kool, Marcel (Author) , Westermann, Frank (Author) , Benner, Axel (Author) , Şeker-Cin, Huriye (Author) , Ryzhova, Marina (Author) , Sturm, Dominik (Author) , Witt, Hendrik (Author) , Haag, Daniel (Author) , Toedt, Grischa (Author) , Wittmann, Andrea (Author) , Schöttler, Anna (Author) , Bueren, André von (Author) , Deimling, Andreas von (Author) , Rutkowski, Stefan (Author) , Scheurlen, Wolfram (Author) , Kulozik, Andreas (Author) , Taylor, Michael D. (Author) , Lichter, Peter (Author) , Pfister, Stefan (Author) ,


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