Corneal allogeneic intrastromal ring segments (CAIRS): the New Kid on the Block = Korneale allogene intrastromale Ringsegmente (CAIRS): The New Kid on the Block

Corneal allogeneic intrastromal ring segments (CAIRS) have recently been introduced as a novel therapeutic modality for keratoconus and corneal ectatic conditions. As with synthetic intracorneal segments, CAIRS are transplanted into intrastromal channel created via femtosecond laser, in order to reg...

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Main Authors: Son, Hyeck Soo (Author) , Augustin, Victor A. (Author) , Friedrich, Maximilian (Author) , Yildirim, Timur Mert (Author) , Khoramnia, Ramin (Author) , Auffarth, Gerd U. (Author)
Format: Article (Journal)
Language:English
Published: 21. August 2025
In: Klinische Monatsblätter für Augenheilkunde
Year: 2025, Volume: 242, Issue: 08, Pages: 803-806
ISSN:1439-3999
DOI:10.1055/a-2621-5109
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1055/a-2621-5109
Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/a-2621-5109
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Author Notes:Hyeck-Soo Son, Victor A. Augustin, Maximilian Friedrich, Timur M. Yildirim, Ramin Khoramnia, Gerd U. Auffarth

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520 |a Corneal allogeneic intrastromal ring segments (CAIRS) have recently been introduced as a novel therapeutic modality for keratoconus and corneal ectatic conditions. As with synthetic intracorneal segments, CAIRS are transplanted into intrastromal channel created via femtosecond laser, in order to regularise the corneal geometry, reduce myopia and astigmatism as well as higher-order aberrations, thus ultimately improving visual and topographic parameters. A growing body of clinical evidence supports the efficacy and safety of this approach, and CAIRS has thus become a paradigm shift in keratoconus treatment. This article provides a brief overview of CAIRS, its surgical indication, and graft preparation and possible customisation. 
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