(68Ga)Ga-FAPI-46 PET/MRI for therapy monitoring of desmoid tumors
Desmoid tumors (DT) are locally aggressive and show a high potential for recurrence. Magnetic resonance imaging (MRI) is the preferred modality for DT staging due to its high soft-tissue contrast. However, MRI was found to have limitations for therapy monitoring. Due to the high expression of fibrob...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
January 2026
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| In: |
Clinical nuclear medicine
Year: 2026, Jahrgang: 51, Heft: 1, Pages: 54-56 |
| ISSN: | 1536-0229 |
| DOI: | 10.1097/RLU.0000000000006194 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/RLU.0000000000006194 Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/nuclearmed/abstract/2026/01000/_68ga_ga_fapi_46_pet_mri_for_therapy_monitoring_of.13.aspx 
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| Verfasserangaben: | Hinterberger, Anna Dr. med. univ, Jakob, Jens Prof. Dr. med, Menge, Franka Dr. med, Davarci, Güllü, Grawe, Freba PD Dr. med |
| Zusammenfassung: | Desmoid tumors (DT) are locally aggressive and show a high potential for recurrence. Magnetic resonance imaging (MRI) is the preferred modality for DT staging due to its high soft-tissue contrast. However, MRI was found to have limitations for therapy monitoring. Due to the high expression of fibroblast activation protein (FAP) in desmoid tumours, positron emission tomography (PET) with FAP inhibitors (FAPI) can serve as an excellent modality for visualizing DT activity. Here, we present the case of a patient with DT undergoing therapy, demonstrating that [68Ga]Ga-FAPI-46 PET holds promise for a more precise therapy monitoring. |
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| Beschreibung: | Im Titel steht der "68Ga" in eckigen Klammern, die Zahl 68 ist dabei hochgestellt Gesehen am 26.01.2026 |
| Beschreibung: | Online Resource |
| ISSN: | 1536-0229 |
| DOI: | 10.1097/RLU.0000000000006194 |