A case of fatal intoxication with the novel synthetic opioid N-pyrrolidino protonitazene
The presence of 2-benzylbenzimidazole-derived opioids (nitazenes) in the drug market is steadily increasing. These often highly potent synthetic opioids can cause severe, potentially fatal effects. This case report presents a fatal intoxication following the vaping of the novel synthetic opioid N-py...
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| Main Authors: | , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
18 October 2025
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| In: |
International journal of legal medicine
Year: 2025, Pages: 1-6 |
| ISSN: | 1437-1596 |
| DOI: | 10.1007/s00414-025-03618-8 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00414-025-03618-8 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00414-025-03618-8?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate |
| Author Notes: | Sophia Wrbas, Tom R. Sundermann, Volker Auwärter, Laura M. Huppertz |
MARC
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| 520 | |a The presence of 2-benzylbenzimidazole-derived opioids (nitazenes) in the drug market is steadily increasing. These often highly potent synthetic opioids can cause severe, potentially fatal effects. This case report presents a fatal intoxication following the vaping of the novel synthetic opioid N-pyrrolidino protonitazene (protonitazepyne), detected in serum obtained 10 h postmortem and in multiple specimens collected at autopsy three days after death. | ||
| 650 | 4 | |a LC-MS/MS | |
| 650 | 4 | |a N-Pyrrolidine protonitazene | |
| 650 | 4 | |a Nitazene | |
| 650 | 4 | |a Novel psychoactive substances (NPS) | |
| 650 | 4 | |a Protonitazepyne | |
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