Overall Survival with Amivantamab-Lazertinib in EGFR-Mutated Advanced NSCLC
In advanced non-small-cell lung cancer with EGFR mutations, amivantamab-lazertinib led to longer overall survival than osimertinib but was associated with an increased risk of adverse events of grade 3 or higher.
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
September 7, 2025
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| In: |
The New England journal of medicine
Year: 2025, Jahrgang: 393, Heft: 17, Pages: 1681-1693 |
| ISSN: | 1533-4406 |
| DOI: | 10.1056/NEJMoa2503001 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1056/NEJMoa2503001 Verlag, lizenzpflichtig, Volltext: https://www.nejm.org/doi/full/10.1056/NEJMoa2503001 
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| Verfasserangaben: | J.C.-H. Yang, S. Lu, H. Hayashi, E. Felip, A.I. Spira, N. Girard, Y.J. Kim, S.-H. Lee, Y. Ostapenko, P. Danchaivijitr, B. Liu, A. Alip, E. Korbenfeld, J. Mourão Dias, B. Besse, A. Passaro, K.-H. Lee, H. Xiong, S.-H. How, Y. Cheng, G.-C. Chang, H. Yoshioka, M. Thomas, D. Nguyen, S.-H.I. Ou, S. Mukhedkar, K. Prabhash, M. D’Arcangelo, J. Alatorre-Alexander, J.C. Vázquez Limón, S. Alves, D. Stroyakovskiy, M. Peregudova, M.A.N. Şendur, O. Yazici, R. Califano, V. Gutiérrez Calderón, F. de Marinis, S.-W. Kim, S.M. Gadgeel, S. Owen, J. Xie, T. Sun, J. Mehta, R. Venkatasubramanian, M. Ennis, E. Fennema, M. Daksh, A. Roshak, J. Man, R.E. Knoblauch, J.M. Bauml, M. Baig, S. Shah, S. Sethi and B.C. Cho, for the MARIPOSA Investigators |
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