Axillary surgery in breast cancer: primary results of the INSEMA trial

This randomized trial involving patients with clinically node-negative, T1 breast cancer showed that the omission of axillary surgery was noninferior to sentinel-lymph-node biopsy.

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Bibliographic Details
Main Authors: Reimer, Toralf (Author) , Stachs, Angrit (Author) , Veselinovic, Kristina (Author) , Kühn, Thorsten (Author) , Heil, Jörg (Author) , Polata, Silke (Author) , Marmé, Frederik (Author) , Müller, Thomas (Author) , Hildebrandt, Guido (Author) , Krug, David (Author) , Ataseven, Beyhan (Author) , Reitsamer, Roland (Author) , Ruth, Sylvia (Author) , Denkert, Carsten (Author) , Bekes, Inga (Author) , Zahm, Dirk-Michael (Author) , Thill, Marc (Author) , Golatta, Michael (Author) , Holtschmidt, Johannes (Author) , Knauer, Michael (Author) , Nekljudova, Valentina (Author) , Loibl, Sibylle (Author) , Gerber, Bernd (Author)
Format: Article (Journal)
Language:English
Published: March 13/20, 2025
In: The New England journal of medicine
Year: 2025, Volume: 392, Issue: 11, Pages: 1051-1064
ISSN:1533-4406
DOI:10.1056/NEJMoa2412063
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1056/NEJMoa2412063
Verlag, lizenzpflichtig, Volltext: https://www.nejm.org/doi/full/10.1056/NEJMoa2412063
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Author Notes:T. Reimer, A. Stachs, K. Veselinovic, T. Kühn, J. Heil, S. Polata, F. Marmé, T. Müller, G. Hildebrandt, D. Krug, B. Ataseven, R. Reitsamer, S. Ruth, C. Denkert, I. Bekes, D.-M. Zahm, M. Thill, M. Golatta, J. Holtschmidt, M. Knauer, V. Nekljudova, S. Loibl and B. Gerber
Description
Summary:This randomized trial involving patients with clinically node-negative, T1 breast cancer showed that the omission of axillary surgery was noninferior to sentinel-lymph-node biopsy.
Item Description:Online veröffentlicht: 12. Dezember 2024
Gesehen am 09.02.2026
Physical Description:Online Resource
ISSN:1533-4406
DOI:10.1056/NEJMoa2412063