Clinical practice, barriers to implementation, and priorities for equitable access of Stereotactic Body Radiation Therapy: an analysis of the global status by the ESTRO SBRT Focus Group

Background - Stereotactic Body Radiation Therapy (SBRT) has become an established treatment for several primary and metastatic malignancies; however, considerable heterogeneity remains in its definition, clinical indications, and technical delivery. - Methods - In May 2025, the SBRT Focus Group of t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Franzese, Ciro (VerfasserIn) , Tanadini-Lang, Stephanie (VerfasserIn) , Verellen, Dirk (VerfasserIn) , Wiersema, Lisa (VerfasserIn) , Hörner-Rieber, Juliane (VerfasserIn) , Romero, Alejandra Méndez (VerfasserIn) , Pasquier, David (VerfasserIn) , Bruynzeel, Anna (VerfasserIn) , Boda-Heggemann, Judit (VerfasserIn) , Depuydt, Tom (VerfasserIn) , Sibolt, Patrik (VerfasserIn) , Douir, Najma (VerfasserIn) , Kuncman, Łukasz (VerfasserIn) , Beijst, Casper (VerfasserIn) , Stephens, Harley (VerfasserIn) , de la Pinta, Carolina (VerfasserIn) , Cuccia, Francesco (VerfasserIn) , Milder, Maaike (VerfasserIn) , Nicosia, Luca (VerfasserIn) , Onishi, Hiroshi (VerfasserIn) , Louie, Alexander V (VerfasserIn) , Sahgal, Arjun (VerfasserIn) , Lo, Simon S (VerfasserIn) , Slotman, Ben J (VerfasserIn) , Guckenberger, Matthias (VerfasserIn) , Scorsetti, Marta (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: March 2026
In: Clinical and translational radiation oncology
Year: 2026, Jahrgang: 57, Pages: 1-7
ISSN:2405-6308
DOI:10.1016/j.ctro.2025.101096
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.ctro.2025.101096
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S2405630825001880
Volltext
Verfasserangaben:Ciro Franzese, Stephanie Tanadini-Lang, Dirk Verellen, Lisa Wiersema, Juliane Hörner-Rieber, Alejandra Méndez Romero, David Pasquier, Anna Bruynzeel, Judit Boda-Heggemann, Tom Depuydt, Patrik Sibolt, Najma Douir, Łukasz Kuncman, Casper Beijst, Harley Stephens, Carolina de la Pinta, Francesco Cuccia, Maaike Milder, Luca Nicosia, Hiroshi Onishi, Alexander V Louie, Arjun Sahgal, Simon S Lo, Ben J Slotman, Matthias Guckenberger, Marta Scorsetti

MARC

LEADER 00000naa a2200000 c 4500
001 1960362070
003 DE-627
005 20260209121659.0
007 cr uuu---uuuuu
008 260209s2026 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.ctro.2025.101096  |2 doi 
035 |a (DE-627)1960362070 
035 |a (DE-599)KXP1960362070 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Franzese, Ciro  |e VerfasserIn  |0 (DE-588)138933712X  |0 (DE-627)1960362402  |4 aut 
245 1 0 |a Clinical practice, barriers to implementation, and priorities for equitable access of Stereotactic Body Radiation Therapy  |b an analysis of the global status by the ESTRO SBRT Focus Group  |c Ciro Franzese, Stephanie Tanadini-Lang, Dirk Verellen, Lisa Wiersema, Juliane Hörner-Rieber, Alejandra Méndez Romero, David Pasquier, Anna Bruynzeel, Judit Boda-Heggemann, Tom Depuydt, Patrik Sibolt, Najma Douir, Łukasz Kuncman, Casper Beijst, Harley Stephens, Carolina de la Pinta, Francesco Cuccia, Maaike Milder, Luca Nicosia, Hiroshi Onishi, Alexander V Louie, Arjun Sahgal, Simon S Lo, Ben J Slotman, Matthias Guckenberger, Marta Scorsetti 
264 1 |c March 2026 
300 |b Illustrationen 
300 |a 7 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Online verfügbar: 14. Dezember 2025, Artikelversion: 18. Dezember 2025 
500 |a Gesehen am 09.02.2026 
520 |a Background - Stereotactic Body Radiation Therapy (SBRT) has become an established treatment for several primary and metastatic malignancies; however, considerable heterogeneity remains in its definition, clinical indications, and technical delivery. - Methods - In May 2025, the SBRT Focus Group of the European Society for Radiotherapy and Oncology (ESTRO), in collaboration with International Stereotactic Radiosurgery Society (ISRS), the Radiosurgery Society (RSS), and the Japanese Society for Radiation Oncology (JASTRO), conducted a global survey. A 44-item questionnaire explored SBRT indications, technical aspects, dose/fractionation, and barriers to implementation. Descriptive statistics summarized the responses. - Results - Overall, 289 professionals from 59 countries participated. Routine use of SBRT was reported by 96.6 % of respondents, with lung, bone, liver and prostate as the most frequent indications. Pancreatic tumor (48.4 %), renal cell carcinoma (46.4 %), and ventricular tachycardia (12.4 %) represented emerging indications. C-arm linacs (89.2 %) and in-room Cone beam CT (CBCT) (92.0 %) were the dominant technologies. Motion management relied mainly on 4D-CT internal target volume (ITV) (88.9 %) and deep inspiration breath-hold (DIBH) (57.8 %). Fractionation was consistent for lung and prostate but heterogeneous for liver, and pancreas. Only 3.5 % reported routine use of online adaptive SBRT, while 61.5 % reported artificial intelligence (AI) use, mainly for organs-at-risk delineation. Key barriers included limited clinical trial funding (35.2 %), high equipment costs (34.2 %), insufficient reimbursement (27.7 %), and workforce shortages (33.9 %). - Conclusions - This ESTRO international survey provides the first global overview of SBRT practices. It demonstrates broad adoption but also substantial variability, highlighting the need for consensus guidelines, greater trial access, and expanded education to harmonize SBRT delivery and ensure equitable care worldwide. 
650 4 |a Ablative radiotherapy 
650 4 |a Advanced radiotherapy 
650 4 |a Radiation oncology 
650 4 |a SABR 
650 4 |a SBRT 
650 4 |a Stereotactic body radiation therapy 
650 4 |a Stereotactic radiotherapy 
700 1 |a Tanadini-Lang, Stephanie  |e VerfasserIn  |4 aut 
700 1 |a Verellen, Dirk  |e VerfasserIn  |4 aut 
700 1 |a Wiersema, Lisa  |e VerfasserIn  |4 aut 
700 1 |a Hörner-Rieber, Juliane  |e VerfasserIn  |4 aut 
700 1 |a Romero, Alejandra Méndez  |e VerfasserIn  |4 aut 
700 1 |a Pasquier, David  |e VerfasserIn  |4 aut 
700 1 |a Bruynzeel, Anna  |e VerfasserIn  |4 aut 
700 1 |a Boda-Heggemann, Judit  |d 1977-  |e VerfasserIn  |0 (DE-588)1029853436  |0 (DE-627)734363087  |0 (DE-576)377699411  |4 aut 
700 1 |a Depuydt, Tom  |e VerfasserIn  |4 aut 
700 1 |a Sibolt, Patrik  |e VerfasserIn  |4 aut 
700 1 |a Douir, Najma  |e VerfasserIn  |4 aut 
700 1 |a Kuncman, Łukasz  |e VerfasserIn  |4 aut 
700 1 |a Beijst, Casper  |e VerfasserIn  |4 aut 
700 1 |a Stephens, Harley  |e VerfasserIn  |4 aut 
700 1 |a de la Pinta, Carolina  |e VerfasserIn  |4 aut 
700 1 |a Cuccia, Francesco  |e VerfasserIn  |4 aut 
700 1 |a Milder, Maaike  |e VerfasserIn  |4 aut 
700 1 |a Nicosia, Luca  |e VerfasserIn  |4 aut 
700 1 |a Onishi, Hiroshi  |e VerfasserIn  |4 aut 
700 1 |a Louie, Alexander V  |e VerfasserIn  |4 aut 
700 1 |a Sahgal, Arjun  |e VerfasserIn  |4 aut 
700 1 |a Lo, Simon S  |e VerfasserIn  |4 aut 
700 1 |a Slotman, Ben J  |e VerfasserIn  |4 aut 
700 1 |a Guckenberger, Matthias  |e VerfasserIn  |4 aut 
700 1 |a Scorsetti, Marta  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Clinical and translational radiation oncology  |d Amsterdam : Elsevier, 2016  |g 57(2026), Artikel-ID 101096, Seite 1-7  |h Online-Ressource  |w (DE-627)880788097  |w (DE-600)2885426-3  |w (DE-576)483742570  |x 2405-6308  |7 nnas  |a Clinical practice, barriers to implementation, and priorities for equitable access of Stereotactic Body Radiation Therapy an analysis of the global status by the ESTRO SBRT Focus Group 
773 1 8 |g volume:57  |g year:2026  |g elocationid:101096  |g pages:1-7  |g extent:7  |a Clinical practice, barriers to implementation, and priorities for equitable access of Stereotactic Body Radiation Therapy an analysis of the global status by the ESTRO SBRT Focus Group 
856 4 0 |u https://doi.org/10.1016/j.ctro.2025.101096  |x Verlag  |x Resolving-System  |z kostenfrei  |3 Volltext  |7 0 
856 4 0 |u https://www.sciencedirect.com/science/article/pii/S2405630825001880  |x Verlag  |z kostenfrei  |3 Volltext  |7 0 
951 |a AR 
992 |a 20260209 
993 |a Article 
994 |a 2026 
998 |g 1029853436  |a Boda-Heggemann, Judit  |m 1029853436:Boda-Heggemann, Judit  |d 60000  |d 63000  |d 60000  |e 60000PB1029853436  |e 63000PB1029853436  |e 60000PB1029853436  |k 0/60000/  |k 1/60000/63000/  |k 0/60000/  |p 9 
999 |a KXP-PPN1960362070  |e 4911504331 
BIB |a Y 
SER |a journal 
JSO |a {"language":["eng"],"person":[{"role":"aut","given":"Ciro","family":"Franzese","display":"Franzese, Ciro"},{"display":"Tanadini-Lang, Stephanie","family":"Tanadini-Lang","given":"Stephanie","role":"aut"},{"role":"aut","given":"Dirk","family":"Verellen","display":"Verellen, Dirk"},{"role":"aut","given":"Lisa","family":"Wiersema","display":"Wiersema, Lisa"},{"display":"Hörner-Rieber, Juliane","family":"Hörner-Rieber","role":"aut","given":"Juliane"},{"family":"Romero","display":"Romero, Alejandra Méndez","given":"Alejandra Méndez","role":"aut"},{"display":"Pasquier, David","family":"Pasquier","role":"aut","given":"David"},{"display":"Bruynzeel, Anna","family":"Bruynzeel","given":"Anna","role":"aut"},{"role":"aut","given":"Judit","display":"Boda-Heggemann, Judit","family":"Boda-Heggemann"},{"display":"Depuydt, Tom","family":"Depuydt","role":"aut","given":"Tom"},{"family":"Sibolt","display":"Sibolt, Patrik","given":"Patrik","role":"aut"},{"family":"Douir","display":"Douir, Najma","role":"aut","given":"Najma"},{"display":"Kuncman, Łukasz","family":"Kuncman","role":"aut","given":"Łukasz"},{"display":"Beijst, Casper","family":"Beijst","given":"Casper","role":"aut"},{"given":"Harley","role":"aut","display":"Stephens, Harley","family":"Stephens"},{"given":"Carolina","role":"aut","display":"de la Pinta, Carolina","family":"de la Pinta"},{"display":"Cuccia, Francesco","family":"Cuccia","role":"aut","given":"Francesco"},{"family":"Milder","display":"Milder, Maaike","given":"Maaike","role":"aut"},{"given":"Luca","role":"aut","display":"Nicosia, Luca","family":"Nicosia"},{"given":"Hiroshi","role":"aut","display":"Onishi, Hiroshi","family":"Onishi"},{"role":"aut","given":"Alexander V","family":"Louie","display":"Louie, Alexander V"},{"family":"Sahgal","display":"Sahgal, Arjun","role":"aut","given":"Arjun"},{"family":"Lo","display":"Lo, Simon S","role":"aut","given":"Simon S"},{"role":"aut","given":"Ben J","family":"Slotman","display":"Slotman, Ben J"},{"given":"Matthias","role":"aut","display":"Guckenberger, Matthias","family":"Guckenberger"},{"given":"Marta","role":"aut","family":"Scorsetti","display":"Scorsetti, Marta"}],"id":{"doi":["10.1016/j.ctro.2025.101096"],"eki":["1960362070"]},"recId":"1960362070","relHost":[{"part":{"extent":"7","text":"57(2026), Artikel-ID 101096, Seite 1-7","volume":"57","pages":"1-7","year":"2026"},"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Clinical practice, barriers to implementation, and priorities for equitable access of Stereotactic Body Radiation Therapy an analysis of the global status by the ESTRO SBRT Focus GroupClinical and translational radiation oncology","origin":[{"dateIssuedDisp":"[2016]-","publisher":"Elsevier","publisherPlace":"Amsterdam"}],"note":["Gesehen am 26.05.2020"],"pubHistory":["Volume 1 (December 2016)-"],"title":[{"title":"Clinical and translational radiation oncology","title_sort":"Clinical and translational radiation oncology"}],"id":{"eki":["880788097"],"zdb":["2885426-3"],"issn":["2405-6308"]},"recId":"880788097","physDesc":[{"extent":"Online-Ressource"}]}],"name":{"displayForm":["Ciro Franzese, Stephanie Tanadini-Lang, Dirk Verellen, Lisa Wiersema, Juliane Hörner-Rieber, Alejandra Méndez Romero, David Pasquier, Anna Bruynzeel, Judit Boda-Heggemann, Tom Depuydt, Patrik Sibolt, Najma Douir, Łukasz Kuncman, Casper Beijst, Harley Stephens, Carolina de la Pinta, Francesco Cuccia, Maaike Milder, Luca Nicosia, Hiroshi Onishi, Alexander V Louie, Arjun Sahgal, Simon S Lo, Ben J Slotman, Matthias Guckenberger, Marta Scorsetti"]},"physDesc":[{"noteIll":"Illustrationen","extent":"7 S."}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Online verfügbar: 14. Dezember 2025, Artikelversion: 18. Dezember 2025","Gesehen am 09.02.2026"],"origin":[{"dateIssuedDisp":"March 2026","dateIssuedKey":"2026"}],"title":[{"subtitle":"an analysis of the global status by the ESTRO SBRT Focus Group","title_sort":"Clinical practice, barriers to implementation, and priorities for equitable access of Stereotactic Body Radiation Therapy","title":"Clinical practice, barriers to implementation, and priorities for equitable access of Stereotactic Body Radiation Therapy"}]} 
SRT |a FRANZESECICLINICALPR2026