The sodium-glucose cotransporter-2 inhibitor canagliflozin alleviates endothelial dysfunction in a rat bypass model
Ischemia/reperfusion (IR) injury during coronary artery bypass grafting surgery has detrimental impacts on endothelial integrity and function. Studies have suggested that canagliflozin (CANA) mitigates the risk of cardiovascular events, independently of diabetes. We hypothesized that the supplementa...
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| Hauptverfasser: | , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
February 2026
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| In: |
Biochemical pharmacology
Year: 2026, Jahrgang: 244, Pages: 1-12 |
| ISSN: | 1873-2968 |
| DOI: | 10.1016/j.bcp.2025.117601 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.bcp.2025.117601 Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0006295225008664 |
| Verfasserangaben: | Ming Ma, Shuo Lian, Patricia Kraft, Tobias Mayer, Alex Ali Sayour, Matthias Karck, Gábor Szabó, Sevil Korkmaz-Icöz |
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