What does not kill you makes you weaker!: Editorial

Tumor cell evasion from regulated cell death is a hallmark of cancer [1]. Davern et al. now identify resistance to mitochondrial apoptosis to represent the common mechanism by which persister cells that survived either immunotherapy- or irradiation-treatment rely on to proliferate. Therefore, they d...

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Hauptverfasser: Maremonti, Francesca (VerfasserIn) , Linkermann, Andreas Günter (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: 05 January 2026
In: Cell death and differentiation
Year: 2026, Pages: 1-2
ISSN:1476-5403
DOI:10.1038/s41418-025-01658-6
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41418-025-01658-6
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41418-025-01658-6
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Verfasserangaben:Francesca Maremonti and Andreas Linkermann
Beschreibung
Zusammenfassung:Tumor cell evasion from regulated cell death is a hallmark of cancer [1]. Davern et al. now identify resistance to mitochondrial apoptosis to represent the common mechanism by which persister cells that survived either immunotherapy- or irradiation-treatment rely on to proliferate. Therefore, they discovered the persister cells´ Achilles heel for future treatments with BH3-mimetics [2].
Beschreibung:Gesehen am 10.02.2026
Beschreibung:Online Resource
ISSN:1476-5403
DOI:10.1038/s41418-025-01658-6