Real word data with no evidence for additional left atrial substrate modification at first PVI procedure in patients with persistent atrial fibrillation: results from the German Ablation registry
Pulmonary vein isolation (PVI) is the cornerstone of interventional treatment for atrial fibrillation. Patients with persistent atrial fibrillation have relatively high recurrence rates after catheter ablation irrespective of treatment strategy. Randomized data suggest that adding substrate modifica...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
23 January 2026
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| In: |
Journal of interventional cardiac electrophysiology
Year: 2026, Pages: 1-9 |
| ISSN: | 1572-8595 |
| DOI: | 10.1007/s10840-025-02212-7 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s10840-025-02212-7 Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s10840-025-02212-7 
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| Author Notes: | Elmar Strzelczyk, Clemens Jilek, Johannes Brachmann, Lars Eckardt, Karl-Heinz Kuck, Stephan Willems, Stefan G. Spitzer, Florian Straube, Burghard Schumacher, Dierk Thomas, Hüseyin Ince, Matthias Hochadel, Jochen Senges, Thorsten Lewalter |
MARC
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| 520 | |a Pulmonary vein isolation (PVI) is the cornerstone of interventional treatment for atrial fibrillation. Patients with persistent atrial fibrillation have relatively high recurrence rates after catheter ablation irrespective of treatment strategy. Randomized data suggest that adding substrate modification to PVI at the first ablation procedure does not improve arrhythmia-free survival. To date, real-world data from experienced centers is limited. | ||
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