Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome: a prospective bicentric study
Annual whole-body MRI (WB-MRI) is recommended for early cancer detection in individuals with Li-Fraumeni syndrome (LFS). However, there is no agreement on a standardized MRI protocol. This study evaluated the diagnostic performance of different MRI sequences to suggest an optimized protocol for LFS...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
21 October 2025
|
| In: |
European radiology
Year: 2025, Pages: 1-12 |
| ISSN: | 1432-1084 |
| DOI: | 10.1007/s00330-025-11880-y |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00330-025-11880-y Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00330-025-11880-y?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate 
|
| Verfasserangaben: | Myriam Margareta Keymling, Felix Tobias Kurz, Tristan Anselm Kuder, Sebastian Bickelhaupt, Thomas Hielscher, Robert Hog, Theresa Mokry, Tawfik Moher Alsady, Sarah Schott, Christian Kratz, Diane Miriam Renz and Heinz-Peter Schlemmer |
MARC
| LEADER | 00000naa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1960952889 | ||
| 003 | DE-627 | ||
| 005 | 20260213092624.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 260213s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00330-025-11880-y |2 doi | |
| 035 | |a (DE-627)1960952889 | ||
| 035 | |a (DE-599)KXP1960952889 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Keymling, Myriam |e VerfasserIn |0 (DE-588)127338928X |0 (DE-627)1823185029 |4 aut | |
| 245 | 1 | 0 | |a Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome |b a prospective bicentric study |c Myriam Margareta Keymling, Felix Tobias Kurz, Tristan Anselm Kuder, Sebastian Bickelhaupt, Thomas Hielscher, Robert Hog, Theresa Mokry, Tawfik Moher Alsady, Sarah Schott, Christian Kratz, Diane Miriam Renz and Heinz-Peter Schlemmer |
| 264 | 1 | |c 21 October 2025 | |
| 300 | |b Illustrationen | ||
| 300 | |a 12 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 13.02.2026 | ||
| 520 | |a Annual whole-body MRI (WB-MRI) is recommended for early cancer detection in individuals with Li-Fraumeni syndrome (LFS). However, there is no agreement on a standardized MRI protocol. This study evaluated the diagnostic performance of different MRI sequences to suggest an optimized protocol for LFS surveillance. | ||
| 650 | 4 | |a Li-Fraumeni syndrome | |
| 650 | 4 | |a Magnetic resonance imaging | |
| 650 | 4 | |a Protocol optimization | |
| 650 | 4 | |a Surveillance | |
| 650 | 4 | |a Whole-body | |
| 700 | 1 | |a Kurz, Felix T. |d 1981- |e VerfasserIn |0 (DE-588)1043285474 |0 (DE-627)771321066 |0 (DE-576)394610342 |4 aut | |
| 700 | 1 | |a Kuder, Tristan Anselm |e VerfasserIn |0 (DE-588)14203911X |0 (DE-627)704126338 |0 (DE-576)326749675 |4 aut | |
| 700 | 1 | |a Bickelhaupt, Sebastian |d 1984- |e VerfasserIn |0 (DE-588)1074040759 |0 (DE-627)83020668X |0 (DE-576)435548131 |4 aut | |
| 700 | 1 | |a Hielscher, Thomas |e VerfasserIn |0 (DE-588)1159594791 |0 (DE-627)1022977768 |0 (DE-576)50506068X |4 aut | |
| 700 | 1 | |a Hog, Robert |e VerfasserIn |0 (DE-588)1216974691 |0 (DE-627)1728639220 |4 aut | |
| 700 | 1 | |a Mokry, Theresa |e VerfasserIn |0 (DE-588)1074843576 |0 (DE-627)832577901 |0 (DE-576)442986297 |4 aut | |
| 700 | 1 | |a Moher Alsady, Tawfik |d 1987- |e VerfasserIn |0 (DE-588)1155631757 |0 (DE-627)1017908109 |0 (DE-576)501795243 |4 aut | |
| 700 | 1 | |a Schott, Sarah |d 1981- |e VerfasserIn |0 (DE-588)133730816 |0 (DE-627)552697281 |0 (DE-576)27460678X |4 aut | |
| 700 | 1 | |a Kratz, Christian Peter |d 1968- |e VerfasserIn |0 (DE-588)120208903 |0 (DE-627)080523536 |0 (DE-576)292097646 |4 aut | |
| 700 | 1 | |a Renz, Diane Miriam Esther |d 1973- |e VerfasserIn |0 (DE-588)130189111 |0 (DE-627)493454160 |0 (DE-576)298052458 |4 aut | |
| 700 | 1 | |a Schlemmer, Heinz-Peter |d 1961- |e VerfasserIn |0 (DE-588)1025559967 |0 (DE-627)722927142 |0 (DE-576)17334805X |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European radiology |d Berlin : Springer, 1991 |g (2025), early access, Seite 1-12 |h Online-Ressource |w (DE-627)268757526 |w (DE-600)1472718-3 |w (DE-576)103868070 |x 1432-1084 |7 nnas |a Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome a prospective bicentric study |
| 773 | 1 | 8 | |g year:2025 |g pages:1-12 |g extent:12 |a Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome a prospective bicentric study |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00330-025-11880-y |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |7 0 |
| 856 | 4 | 0 | |u https://link.springer.com/article/10.1007/s00330-025-11880-y?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate |x Verlag |z kostenfrei |3 Volltext |7 0 |
| 951 | |a AR | ||
| 992 | |a 20260213 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 1025559967 |a Schlemmer, Heinz-Peter |m 1025559967:Schlemmer, Heinz-Peter |d 50000 |e 50000PS1025559967 |k 0/50000/ |p 13 |y j | ||
| 998 | |g 133730816 |a Schott, Sarah |m 133730816:Schott, Sarah |d 910000 |d 910400 |e 910000PS133730816 |e 910400PS133730816 |k 0/910000/ |k 1/910000/910400/ |p 8 | ||
| 998 | |g 1074843576 |a Mokry, Theresa |m 1074843576:Mokry, Theresa |d 910000 |d 911400 |e 910000PM1074843576 |e 911400PM1074843576 |k 0/910000/ |k 1/910000/911400/ |p 7 | ||
| 998 | |g 1216974691 |a Hog, Robert |m 1216974691:Hog, Robert |d 50000 |e 50000PH1216974691 |k 0/50000/ |p 6 | ||
| 998 | |g 1159594791 |a Hielscher, Thomas |m 1159594791:Hielscher, Thomas |d 50000 |e 50000PH1159594791 |k 0/50000/ |p 5 | ||
| 998 | |g 14203911X |a Kuder, Tristan Anselm |m 14203911X:Kuder, Tristan Anselm |d 130000 |e 130000PK14203911X |k 0/130000/ |p 3 | ||
| 998 | |g 1043285474 |a Kurz, Felix T. |m 1043285474:Kurz, Felix T. |d 50000 |e 50000PK1043285474 |k 0/50000/ |p 2 | ||
| 998 | |g 127338928X |a Keymling, Myriam |m 127338928X:Keymling, Myriam |p 1 |x j | ||
| 999 | |a KXP-PPN1960952889 |e 4915680460 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"bibl":"article-journal","media":"Online-Ressource"},"person":[{"display":"Keymling, Myriam","role":"aut","given":"Myriam","family":"Keymling"},{"family":"Kurz","given":"Felix T.","display":"Kurz, Felix T.","role":"aut"},{"display":"Kuder, Tristan Anselm","role":"aut","family":"Kuder","given":"Tristan Anselm"},{"family":"Bickelhaupt","given":"Sebastian","display":"Bickelhaupt, Sebastian","role":"aut"},{"role":"aut","display":"Hielscher, Thomas","given":"Thomas","family":"Hielscher"},{"role":"aut","display":"Hog, Robert","given":"Robert","family":"Hog"},{"family":"Mokry","given":"Theresa","role":"aut","display":"Mokry, Theresa"},{"given":"Tawfik","family":"Moher Alsady","role":"aut","display":"Moher Alsady, Tawfik"},{"family":"Schott","given":"Sarah","role":"aut","display":"Schott, Sarah"},{"role":"aut","display":"Kratz, Christian Peter","family":"Kratz","given":"Christian Peter"},{"role":"aut","display":"Renz, Diane Miriam Esther","family":"Renz","given":"Diane Miriam Esther"},{"family":"Schlemmer","given":"Heinz-Peter","display":"Schlemmer, Heinz-Peter","role":"aut"}],"language":["eng"],"id":{"eki":["1960952889"],"doi":["10.1007/s00330-025-11880-y"]},"note":["Gesehen am 13.02.2026"],"relHost":[{"language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"id":{"issn":["1432-1084","1613-3757"],"zdb":["1472718-3"],"eki":["268757526"]},"disp":"Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome a prospective bicentric studyEuropean radiology","physDesc":[{"extent":"Online-Ressource"}],"pubHistory":["1.1991 -"],"title":[{"title":"European radiology","title_sort":"European radiology","subtitle":"official organ of the European Association of Radiology"}],"note":["Gesehen am 06.02.2018","Ungezählte Beil.: Supplement"],"part":{"extent":"12","text":"(2025), early access, Seite 1-12","year":"2025","pages":"1-12"},"titleAlt":[{"title":"European radiology / Supplement"},{"title":"European radiology supplements"}],"corporate":[{"display":"European Association of Radiology","role":"isb"}],"origin":[{"dateIssuedKey":"1991","publisher":"Springer","dateIssuedDisp":"1991-","publisherPlace":"Berlin ; Heidelberg"}],"recId":"268757526"}],"name":{"displayForm":["Myriam Margareta Keymling, Felix Tobias Kurz, Tristan Anselm Kuder, Sebastian Bickelhaupt, Thomas Hielscher, Robert Hog, Theresa Mokry, Tawfik Moher Alsady, Sarah Schott, Christian Kratz, Diane Miriam Renz and Heinz-Peter Schlemmer"]},"origin":[{"dateIssuedDisp":"21 October 2025","dateIssuedKey":"2025"}],"physDesc":[{"noteIll":"Illustrationen","extent":"12 S."}],"title":[{"subtitle":"a prospective bicentric study","title_sort":"Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome","title":"Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome"}],"recId":"1960952889"} | ||
| SRT | |a KEYMLINGMYOPTIMIZING2120 | ||