Validation of novel low-dose CT methods for quantifying bone marrow in the appendicular skeleton of patients with multiple myeloma: initial results from the [¹⁸F]FDG PET/CT sub-study of the Phase 3 GMMG-HD7 Trial
The clinical significance of medullary abnormalities in the appendicular skeleton detected by computed tomography (CT) in patients with multiple myeloma (MM) remains incompletely elucidated. This study aims to validate novel low-dose CT-based methods for quantifying myeloma bone marrow (BM) volume i...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
1 October 2025
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| In: |
European journal of nuclear medicine and molecular imaging
Year: 2026, Jahrgang: 53, Heft: 3, Pages: 1509-1520 |
| ISSN: | 1619-7089 |
| DOI: | 10.1007/s00259-025-07599-z |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-025-07599-z
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| Verfasserangaben: | Christos Sachpekidis, Marina Hajiyianni, Martin Grözinger, Maja Piller, Annette Kopp-Schneider, Elias K. Mai, Lukas John, Sandra Sauer, Niels Weinhold, Ekaterina Menis, Olof Enqvist, Marc S. Raab, Anna Jauch, Lars Edenbrandt, Michael Hundemer, Alexander Brobeil, Johann Jende, Heinz-Peter Schlemmer, Stefan Delorme, Hartmut Goldschmidt, Antonia Dimitrakopoulou-Strauss |
MARC
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| 245 | 1 | 0 | |a Validation of novel low-dose CT methods for quantifying bone marrow in the appendicular skeleton of patients with multiple myeloma |b initial results from the [¹⁸F]FDG PET/CT sub-study of the Phase 3 GMMG-HD7 Trial |c Christos Sachpekidis, Marina Hajiyianni, Martin Grözinger, Maja Piller, Annette Kopp-Schneider, Elias K. Mai, Lukas John, Sandra Sauer, Niels Weinhold, Ekaterina Menis, Olof Enqvist, Marc S. Raab, Anna Jauch, Lars Edenbrandt, Michael Hundemer, Alexander Brobeil, Johann Jende, Heinz-Peter Schlemmer, Stefan Delorme, Hartmut Goldschmidt, Antonia Dimitrakopoulou-Strauss |
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| 520 | |a The clinical significance of medullary abnormalities in the appendicular skeleton detected by computed tomography (CT) in patients with multiple myeloma (MM) remains incompletely elucidated. This study aims to validate novel low-dose CT-based methods for quantifying myeloma bone marrow (BM) volume in the appendicular skeleton of MM patients undergoing [18F]FDG PET/CT. | ||
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| 650 | 4 | |a Induction therapy | |
| 650 | 4 | |a Isatuximab | |
| 650 | 4 | |a Italian Myeloma criteria for PET Use (IMPeTUs) | |
| 650 | 4 | |a Minimal residual disease (MRD) | |
| 650 | 4 | |a Multiple myeloma | |
| 650 | 4 | |a Whole-body low-dose CT | |
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