Biofilm formation by the global outbreak strain of Mycobacterium chimaera results in significantly reduced efficacy of standard disinfectants
In 2013, a global outbreak of Mycobacterium chimaera infections due to contaminated heater-cooler units emerged. This ongoing problem has highlighted the question of whether disinfection recommendations for medical devices containing water circuits are adequate for preventing contamination and possi...
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| Main Authors: | , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
13 November 2025
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| In: |
BMC microbiology
Year: 2025, Volume: 25, Issue: 1, Pages: 1-12 |
| ISSN: | 1471-2180 |
| DOI: | 10.1186/s12866-025-04439-w |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12866-025-04439-w Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1186/s12866-025-04439-w 
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| Author Notes: | Anna Maria Oschmann, Katharina Konrat, Christoph Schaudinn, Genevieve Sohl, Dirk Wagner, Astrid Lewin and Mardjan Arvand |
| Summary: | In 2013, a global outbreak of Mycobacterium chimaera infections due to contaminated heater-cooler units emerged. This ongoing problem has highlighted the question of whether disinfection recommendations for medical devices containing water circuits are adequate for preventing contamination and possible recontamination by nontuberculous mycobacteria. The formation of biofilms in such devices exacerbates the problem. This study aimed to assess the efficacy of disinfectants on biofilms and suspensions of the M. chimaera strain ZUERICH-1, and to compare it with two unrelated M. chimaera strains obtained from different sources. |
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| Item Description: | Gesehen am 19.02.2026 |
| Physical Description: | Online Resource |
| ISSN: | 1471-2180 |
| DOI: | 10.1186/s12866-025-04439-w |