Survival in patients with chronic thromboembolic pulmonary hypertension treated with riociguat versus other medications: a COMPERA analysis
Extract: Current treatment options for patients with chronic thromboembolic pulmonary hypertension (CTEPH) include surgical pulmonary endarterectomy (PEA), interventional balloon pulmonary angioplasty (BPA) and medical therapy [1, 2]. For many years, medical treatment primarily involved off-label us...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
8 December 2025
|
| In: |
ERJ Open Research
Year: 2025, Jahrgang: 11, Heft: 6, Pages: 1-5 |
| ISSN: | 2312-0541 |
| DOI: | 10.1183/23120541.00230-2025 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1183/23120541.00230-2025 Verlag, kostenfrei, Volltext: https://publications.ersnet.org/content/erjor/11/6/00230-2025 
|
| Verfasserangaben: | Matthias Held, Christine Pausch, Doerte Huscher, David Pittrow, Michael Halank, Stephan Beckmann, Stefan Stadler, Khodr Tello, Ekkehard Grünig, Christian Opitz, Marion Delcroix, H. Ardeschir Ghofrani, Juergen Behr, Andris Skride, Dirk Skowasch, Anton Vonk-Noordegraaf, Silvia Ulrich, Hans Klose, Stephan Rosenkranz, Karen M. Olsson, Marius M. Hoeper and Grzegorz Kopec |
MARC
| LEADER | 00000naa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1961858320 | ||
| 003 | DE-627 | ||
| 005 | 20260220101538.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 260220s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1183/23120541.00230-2025 |2 doi | |
| 035 | |a (DE-627)1961858320 | ||
| 035 | |a (DE-599)KXP1961858320 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Held, Matthias |d 1969- |e VerfasserIn |0 (DE-588)121547949 |0 (DE-627)70552809X |0 (DE-576)188881727 |4 aut | |
| 245 | 1 | 0 | |a Survival in patients with chronic thromboembolic pulmonary hypertension treated with riociguat versus other medications |b a COMPERA analysis |c Matthias Held, Christine Pausch, Doerte Huscher, David Pittrow, Michael Halank, Stephan Beckmann, Stefan Stadler, Khodr Tello, Ekkehard Grünig, Christian Opitz, Marion Delcroix, H. Ardeschir Ghofrani, Juergen Behr, Andris Skride, Dirk Skowasch, Anton Vonk-Noordegraaf, Silvia Ulrich, Hans Klose, Stephan Rosenkranz, Karen M. Olsson, Marius M. Hoeper and Grzegorz Kopec |
| 264 | 1 | |c 8 December 2025 | |
| 300 | |b Illustrationen | ||
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Online veröffentlicht: 8. Dezember 2025 | ||
| 500 | |a Gesehen am 20.02.2026 | ||
| 520 | |a Extract: Current treatment options for patients with chronic thromboembolic pulmonary hypertension (CTEPH) include surgical pulmonary endarterectomy (PEA), interventional balloon pulmonary angioplasty (BPA) and medical therapy [1, 2]. For many years, medical treatment primarily involved off-label use of drugs approved for pulmonary arterial hypertension, despite limited and sometimes inconclusive evidence supporting their effectiveness in CTEPH patients. In 2014, riociguat, a soluble guanylate cyclase stimulator, became the first drug approved for treating patients with inoperable CTEPH or persistent/recurrent pulmonary hypertension (PH) post-surgery [3]. Parenteral treprostinil was subsequently approved for CTEPH [4], although its use has remained limited, likely due to the invasiveness and associated side-effects. | ||
| 700 | 1 | |a Pausch, Christine |e VerfasserIn |4 aut | |
| 700 | 1 | |a Huscher, Doerte |e VerfasserIn |4 aut | |
| 700 | 1 | |a Pittrow, David |e VerfasserIn |4 aut | |
| 700 | 1 | |a Halank, Michael |e VerfasserIn |4 aut | |
| 700 | 1 | |a Beckmann, Stephan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Stadler, Stefan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tello, Khodr |e VerfasserIn |4 aut | |
| 700 | 1 | |a Grünig, Ekkehard |e VerfasserIn |0 (DE-588)112535801 |0 (DE-627)618892605 |0 (DE-576)31856694X |4 aut | |
| 700 | 1 | |a Opitz, Christian |e VerfasserIn |4 aut | |
| 700 | 1 | |a Delcroix, Marion |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ghofrani, H. Ardeschir |e VerfasserIn |4 aut | |
| 700 | 1 | |a Behr, Juergen |e VerfasserIn |4 aut | |
| 700 | 1 | |a Skride, Andris |e VerfasserIn |4 aut | |
| 700 | 1 | |a Skowasch, Dirk |e VerfasserIn |4 aut | |
| 700 | 1 | |a Vonk-Noordegraaf, Anton |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ulrich, Silvia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Klose, Hans |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rosenkranz, Stephan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Olsson, Karen M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hoeper, Marius M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kopec, Grzegorz |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t ERJ Open Research |d [Erscheinungsort nicht ermittelbar] : European Respiratory Society, 2015 |g 11(2025), 6, Artikel-ID 00230-2025, Seite 1-5 |h Online-Ressource |w (DE-627)830141227 |w (DE-600)2827830-6 |w (DE-576)435330136 |x 2312-0541 |7 nnas |a Survival in patients with chronic thromboembolic pulmonary hypertension treated with riociguat versus other medications a COMPERA analysis |
| 773 | 1 | 8 | |g volume:11 |g year:2025 |g number:6 |g elocationid:00230-2025 |g pages:1-5 |g extent:5 |a Survival in patients with chronic thromboembolic pulmonary hypertension treated with riociguat versus other medications a COMPERA analysis |
| 856 | 4 | 0 | |u https://doi.org/10.1183/23120541.00230-2025 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |7 0 |
| 856 | 4 | 0 | |u https://publications.ersnet.org/content/erjor/11/6/00230-2025 |x Verlag |z kostenfrei |3 Volltext |7 0 |
| 951 | |a AR | ||
| 992 | |a 20260220 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 112535801 |a Grünig, Ekkehard |m 112535801:Grünig, Ekkehard |d 910000 |d 950000 |d 950900 |d 50000 |e 910000PG112535801 |e 950000PG112535801 |e 950900PG112535801 |e 50000PG112535801 |k 0/910000/ |k 1/910000/950000/ |k 2/910000/950000/950900/ |k 0/50000/ |p 9 | ||
| 999 | |a KXP-PPN1961858320 |e 492052630X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1961858320","relHost":[{"type":{"media":"Online-Ressource","bibl":"periodical"},"pubHistory":["1.2015 -"],"recId":"830141227","disp":"Survival in patients with chronic thromboembolic pulmonary hypertension treated with riociguat versus other medications a COMPERA analysisERJ Open Research","physDesc":[{"extent":"Online-Ressource"}],"corporate":[{"display":"European Respiratory Society","role":"isb"}],"id":{"issn":["2312-0541"],"zdb":["2827830-6"],"eki":["830141227"]},"title":[{"title":"ERJ Open Research","title_sort":"ERJ Open Research","subtitle":"the best in open access basic, translational & clinical respiratory research"}],"language":["eng"],"name":{"displayForm":["European Respiratory Society"]},"part":{"year":"2025","volume":"11","extent":"5","pages":"1-5","issue":"6","text":"11(2025), 6, Artikel-ID 00230-2025, Seite 1-5"},"origin":[{"dateIssuedKey":"2015","publisherPlace":"[Erscheinungsort nicht ermittelbar]","dateIssuedDisp":"2015-","publisher":"European Respiratory Society"}],"note":["Gesehen am 31.10.24"]}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"eki":["1961858320"],"doi":["10.1183/23120541.00230-2025"]},"language":["eng"],"title":[{"subtitle":"a COMPERA analysis","title":"Survival in patients with chronic thromboembolic pulmonary hypertension treated with riociguat versus other medications","title_sort":"Survival in patients with chronic thromboembolic pulmonary hypertension treated with riociguat versus other medications"}],"physDesc":[{"extent":"5 S.","noteIll":"Illustrationen"}],"origin":[{"dateIssuedKey":"2025","dateIssuedDisp":"8 December 2025"}],"name":{"displayForm":["Matthias Held, Christine Pausch, Doerte Huscher, David Pittrow, Michael Halank, Stephan Beckmann, Stefan Stadler, Khodr Tello, Ekkehard Grünig, Christian Opitz, Marion Delcroix, H. Ardeschir Ghofrani, Juergen Behr, Andris Skride, Dirk Skowasch, Anton Vonk-Noordegraaf, Silvia Ulrich, Hans Klose, Stephan Rosenkranz, Karen M. Olsson, Marius M. Hoeper and Grzegorz Kopec"]},"person":[{"display":"Held, Matthias","role":"aut","given":"Matthias","family":"Held"},{"role":"aut","display":"Pausch, Christine","family":"Pausch","given":"Christine"},{"role":"aut","display":"Huscher, Doerte","family":"Huscher","given":"Doerte"},{"display":"Pittrow, David","role":"aut","family":"Pittrow","given":"David"},{"family":"Halank","given":"Michael","role":"aut","display":"Halank, Michael"},{"display":"Beckmann, Stephan","role":"aut","family":"Beckmann","given":"Stephan"},{"family":"Stadler","given":"Stefan","role":"aut","display":"Stadler, Stefan"},{"family":"Tello","given":"Khodr","display":"Tello, Khodr","role":"aut"},{"display":"Grünig, Ekkehard","role":"aut","family":"Grünig","given":"Ekkehard"},{"family":"Opitz","given":"Christian","role":"aut","display":"Opitz, Christian"},{"family":"Delcroix","given":"Marion","display":"Delcroix, Marion","role":"aut"},{"given":"H. Ardeschir","family":"Ghofrani","display":"Ghofrani, H. Ardeschir","role":"aut"},{"family":"Behr","given":"Juergen","display":"Behr, Juergen","role":"aut"},{"role":"aut","display":"Skride, Andris","given":"Andris","family":"Skride"},{"family":"Skowasch","given":"Dirk","display":"Skowasch, Dirk","role":"aut"},{"given":"Anton","family":"Vonk-Noordegraaf","role":"aut","display":"Vonk-Noordegraaf, Anton"},{"given":"Silvia","family":"Ulrich","display":"Ulrich, Silvia","role":"aut"},{"given":"Hans","family":"Klose","display":"Klose, Hans","role":"aut"},{"family":"Rosenkranz","given":"Stephan","role":"aut","display":"Rosenkranz, Stephan"},{"given":"Karen M.","family":"Olsson","display":"Olsson, Karen M.","role":"aut"},{"family":"Hoeper","given":"Marius M.","role":"aut","display":"Hoeper, Marius M."},{"given":"Grzegorz","family":"Kopec","role":"aut","display":"Kopec, Grzegorz"}],"note":["Online veröffentlicht: 8. Dezember 2025","Gesehen am 20.02.2026"]} | ||
| SRT | |a HELDMATTHISURVIVALIN8202 | ||