Soft X-ray tomography illuminates drug-induced changes in insulin granules
In this issue of Structure, Deshmukh et al.1 reveal that β cells actively remodel insulin secretory granules in response to specific physiological cues, altering granule density, proinsulin processing, and spatial distribution. This stimulus-specific structural maturation highlights how β cells scul...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
6 November 2025
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| In: |
Structure
Year: 2025, Jahrgang: 33, Heft: 11, Pages: 1813-1815 |
| ISSN: | 1878-4186 |
| DOI: | 10.1016/j.str.2025.10.007 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.str.2025.10.007 Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0969212625003946 
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| Verfasserangaben: | Natalia Fuchs and Venera Weinhardt |
| Zusammenfassung: | In this issue of Structure, Deshmukh et al.1 reveal that β cells actively remodel insulin secretory granules in response to specific physiological cues, altering granule density, proinsulin processing, and spatial distribution. This stimulus-specific structural maturation highlights how β cells sculpt their secretory machinery, offering new insights into insulin release regulation. |
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| Beschreibung: | Online verfügbar 6 November 2025, Version des Artikels 6 November 2025 Gesehen am 20.02.2026 |
| Beschreibung: | Online Resource |
| ISSN: | 1878-4186 |
| DOI: | 10.1016/j.str.2025.10.007 |