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Quantitative analysis of chest computed tomography in alpha-1-antitrypsin deficiency

Chest quantitative computed tomography (QCT) has been used in clinical trials to monitor patients with alpha-1 antitrypsin deficiency (AATD). There is limited data on the use of quantitative computed tomography (QCT) to phenotype emphysema in AATD.

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Bibliographic Details
Main Authors: Höger, Philipp (Author) , Benholz, Johanna (Author) , Weinheimer, Oliver (Author) , Wielpütz, Mark Oliver (Author) , Heußel, Claus Peter (Author) , Bischoff, Arved (Author) , Eberhardt, Ralf (Author) , Buschulte, Katharina (Author) , Fähndrich, Sebastian (Author) , Michels-Zetsche, Julia D. (Author) , Ersöz, Hilal (Author) , Olivares-Rivera, Arturo (Author) , Herth, Felix (Author) , Trudzinski, Franziska (Author)
Format: Article (Journal)
Language:English
Published: 15 November 2025
In: Respiratory research
Year: 2025, Volume: 26, Pages: 1-10
ISSN:1465-993X
DOI:10.1186/s12931-025-03413-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12931-025-03413-4
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Author Notes:Philipp Höger, Johanna Benholz, Oliver Weinheimer, Mark Oliver Wielpütz, Claus Peter Heußel, Arved Bischoff, Ralf Eberhardt, Katharina Buschulte, Sebastian Fähndrich, Julia D. Michels-Zetsche, Hilal Ersöz, Arturo Olivares Rivera, Felix Herth and Franziska C. Trudzinski
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Summary:Chest quantitative computed tomography (QCT) has been used in clinical trials to monitor patients with alpha-1 antitrypsin deficiency (AATD). There is limited data on the use of quantitative computed tomography (QCT) to phenotype emphysema in AATD.
Item Description:Gesehen am 25.02.2026
Physical Description:Online Resource
ISSN:1465-993X
DOI:10.1186/s12931-025-03413-4

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