Repulsive particle interactions enable selective information processing at cellular interfaces
Living systems relay information across membrane interfaces to coordinate compartment functions. We identify a physical mechanism for selective information transmission that arises from the sigmoidal response of surface-bound particle densities to spatial features in adjacent external structures thr...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
21 November 2025
|
| In: |
Physical review letters
Year: 2025, Volume: 135, Issue: 21, Pages: 1-9 |
| ISSN: | 1079-7114 |
| DOI: | 10.1103/ywr6-mzz5 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1103/ywr6-mzz5 Verlag, kostenfrei, Volltext: https://link.aps.org/doi/10.1103/ywr6-mzz5 
|
| Author Notes: | J. Elliott, H. Shah, R. Belousov, G. Dey, and A. Erzberger |
| Summary: | Living systems relay information across membrane interfaces to coordinate compartment functions. We identify a physical mechanism for selective information transmission that arises from the sigmoidal response of surface-bound particle densities to spatial features in adjacent external structures through a nonuniform binding energy. This mechanism implements a form of spatial thresholding, enabling the binary classification of external cues. Expansion microscopy measurements of nuclear pore complex distributions in S. arctica show signatures of such physical thresholding. |
|---|---|
| Item Description: | Gesehen am 25.02.2026 |
| Physical Description: | Online Resource |
| ISSN: | 1079-7114 |
| DOI: | 10.1103/ywr6-mzz5 |