Roles of catecholamines and inflammation in endothelial dysfunction: a study using Takotsubo syndrome patient-specific hiPSC-ECs
Takotsubo syndrome (TTS), also known as stress-induced cardiomyopathy, is characterized by transient left ventricular dysfunction often triggered by emotional or physical stress. Catecholamines are believed to play a pivotal role in the pathogenesis of TTS, including endothelial dysfunction. This st...
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| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
06 February 2026
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| In: |
Stem cell reviews and reports
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| ISSN: | 2629-3277 |
| DOI: | 10.1007/s12015-026-11059-y |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s12015-026-11059-y
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| Verfasserangaben: | Guoqiang Yang, Luyi Zhong, Jiayue Wang, Chenyu Yang, Lukas Cyganek, Nazha Hamdani, Xiaobo Zhou, Xuehui Fan, Ibrahim El-Battrawy, Ibrahim Akin |
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| 520 | |a Takotsubo syndrome (TTS), also known as stress-induced cardiomyopathy, is characterized by transient left ventricular dysfunction often triggered by emotional or physical stress. Catecholamines are believed to play a pivotal role in the pathogenesis of TTS, including endothelial dysfunction. This study aimed to elucidate the catecholamine-induced endothelial dysfunction using patient-specific induced pluripotent stem cell-derived endothelial cells (hiPSC-ECs) from TTS patients. | ||
| 650 | 4 | |a Catecholamine excess | |
| 650 | 4 | |a Endothelial dysfunction | |
| 650 | 4 | |a Human induced pluripotent stem cell-derived endothelial cells | |
| 650 | 4 | |a Inflammation | |
| 650 | 4 | |a Takotsubo syndrome | |
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