High versus low pneumoperitoneum PressUre for parenchymal transection in minimally invasive major liver surgery (PPULS): a non-inferiority, multicenter, randomized, controlled trial
Low pneumoperitoneum pressure (LPP) lowers the incidence of CO2 embolisms in minimally invasive liver resections (MILR), while higher pneumoperitoneum pressure (HPP) reduces intraoperative blood loss. This contradiction necessitates careful pressure management especially in major liver resections wh...
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
01 December 2025
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| In: |
Trials
Year: 2025, Jahrgang: 26, Heft: 1 |
| ISSN: | 1468-6694 |
| DOI: | 10.1186/s13063-025-09269-9 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13063-025-09269-9 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1186/s13063-025-09269-9 
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| Verfasserangaben: | Esther Giehl-Brown, Elias Khajeh, Sarah Dehne, Zoltan Czigany, Oliver Gutzeit, Christopher Neuhaus, Carina Riediger, Emrullah Birgin, Nuh Rahbari, Mathieu D’Hondt, Georg Lurje, Markus Weigand, Christoph Michalski, Arianeb Mehrabi and Christoph Kahlert |
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| 520 | |a Low pneumoperitoneum pressure (LPP) lowers the incidence of CO2 embolisms in minimally invasive liver resections (MILR), while higher pneumoperitoneum pressure (HPP) reduces intraoperative blood loss. This contradiction necessitates careful pressure management especially in major liver resections where intraoperative blood loss greatly impacts postoperative outcome. | ||
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| 650 | 4 | |a Parenchymal dissection | |
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