Low tumour burden is associated with observation after surgery in patients with grade 2 astrocytoma and oligodendroglioma: results from the prospective multicentre LoG-Glio registry

Recent evidence-based guidelines recommend adjuvant therapy following surgery for most patients with WHO grade 2 and 3 gliomas. However, deviations from these recommendations are frequently observed in clinical practice. This study aimed to evaluate patterns of postoperative management across German...

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Main Authors: Ziebart, Andreas (Author) , Onken, Julia Sophie (Author) , Nadji-Ohl, Minou (Author) , Jungk, Christine (Author) , rückriegel, Stefan (Author) , Wachter, Dorothee (Author) , Gerlach, Rüdiger (Author) , Forster, Marie-Thérèse (Author) , Roder, Constantin (Author) , Kniese, Katja (Author) , Neidert, Nicolas (Author) , Fabbrocini, Ludovica (Author) , Kalasauskas, Darius (Author) , Aziz, Gerges (Author) , Riehl, Sabrina (Author) , Sannwald, Lennart (Author) , Mayer, Benjamin (Author) , Wirtz, Christian Rainer (Author) , Sachs, Daniel (Author) , Ille, Sebastian (Author) , Löhr, Mario (Author) , Ritz, Rainer (Author) , Ringel, Florian (Author) , Ebner, Florian (Author) , Rölz, Roland (Author) , Beck, Jürgen (Author) , Nabavi, Arya (Author) , Tatagiba, Marcos (Author) , Czabanka, Marcus (Author) , Rohde, Veit (Author) , Ernestus, Ralf-Ingo (Author) , Krieg, Sandro (Author) , Ganslandt, Oliver (Author) , Vajkoczy, Peter (Author) , Coburger, Jan (Author)
Format: Article (Journal)
Language:English
Published: 15 October 2025
In: Journal of neuro-oncology
Year: 2025, Volume: 176, Issue: 1, Pages: 1-10
ISSN:1573-7373
DOI:10.1007/s11060-025-05279-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s11060-025-05279-4
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s11060-025-05279-4?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate
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Author Notes:Andreas Ziebart, Julia Onken, Minou Nadji-Ohl, Christine Jungk, Stefan Rückriegel, Dorothee Mielke, Rüdiger Gerlach, Marie-Therese Forster, Constantin Roder, Katja Kniese, Nicolas Neidert, Ludovica Fabbrocini, Darius Kalasauskas, Gerges Aziz, Sabrina Riehl, Lennart Sannwald, Benjamin Mayer, Christian Rainer Wirtz, Daniel Sachs, Sebastian Ille, Mario Löhr, Rainer Ritz, Florian Ringel, Florian Ebner, Roland Roelz, Jürgen Beck, Arya Nabavi, Marcos Tatagiba, Marcus Czabanka, Veit Rohde, Ralf-Ingo Ernestus, Sandro Krieg, Oliver Ganslandt, Peter Vajkoczy, Jan Coburger
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Summary:Recent evidence-based guidelines recommend adjuvant therapy following surgery for most patients with WHO grade 2 and 3 gliomas. However, deviations from these recommendations are frequently observed in clinical practice. This study aimed to evaluate patterns of postoperative management across Germany, using multicentre registry data from certified neuro-oncology centres.
Item Description:Gesehen am 27.02.2026
Physical Description:Online Resource
ISSN:1573-7373
DOI:10.1007/s11060-025-05279-4