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Lecanemab for treatment of individuals with early Alzheimer’s Disease (AD) who are apolipoprotein E ε4 (ApoE ε4) non-carriers or heterozygotes

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Background - Lecanemab, an antibody directed at Aβ-protofibrils and plaque, showed meaningful delay in disease progression and biological effects consistent with disease modification in the phase 3 Clarity AD trial. - Objective - The objective of this paper is to present efficacy and safety results...

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Main Authors: Perry, Richard (Author) , Kipps, Christopher (Author) , Soto Martín, Maria Eugenia (Author) , Bozzali, Marco (Author) , Logroscino, Giancarlo (Author) , Trafford, Sarah (Author) , Dhadda, Shobha (Author) , Kanekiyo, Michio (Author) , Goodwin, Amanda (Author) , Hodgkinson, Mark (Author) , Hersch, Steven (Author) , Irizarry, Michael (Author) , Kramer, Lynn (Author) , Frölich, Lutz (Author)
Format: Article (Journal)
Language:English
Published: April 2026
In: The journal of prevention of Alzheimer's disease
Year: 2026, Volume: 13, Issue: 4, Pages: 1-11
ISSN:2426-0266
DOI:10.1016/j.tjpad.2026.100507
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.tjpad.2026.100507
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S2274580726000312
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Author Notes:Richard Perry, Christopher Kipps, Maria Eugenia Soto Martín, Marco Bozzali, Giancarlo Logroscino, Sarah Trafford, Shobha Dhadda, Michio Kanekiyo, Amanda Goodwin, Mark Hodgkinson, Steven Hersch, Michael Irizarry, Lynn Kramer, Lutz Froelich
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Corrigendum to “Lecanemab for treatment of individuals with early Alzheimer’s Disease (AD) who are apolipoprotein E ε4 (ApoE ε4) non-carriers or heterozygotes” (The Journal of Prev... by Perry, Richard (Author) , Kipps, Christopher (Author) , Martín, Maria Eugenia Soto (Author) , Bozzali, Marco (Author) , Logroscino, Giancarlo (Author) , Trafford, Sarah (Author) , Dhadda, Shobha (Author) , Kanekiyo, Michio (Author) , Goodwin, Amanda (Author) , Hodgkinson, Mark (Author) , Hersch, Steven (Author) , Irizarry, Michael (Author) , Kramer, Lynn (Author) , Frölich, Lutz (Author) ,


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