Adaptive validation strategies for real-world clinical artificial intelligence

Technical metrics used to evaluate medical artificial intelligence tools often fail to predict their clinical impact. We characterize this discordance and propose a framework of study designs to guide the translational process for clinical artificial intelligence tools, acknowledging their diversity...

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Hauptverfasser: Kolbinger, Fiona (VerfasserIn) , Kather, Jakob Nikolas (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: 17 November 2025
In: Nature computational science
Year: 2025, Jahrgang: 5, Heft: 11, Pages: 980-986
ISSN:2662-8457
DOI:10.1038/s43588-025-00901-x
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s43588-025-00901-x
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s43588-025-00901-x
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Verfasserangaben:Fiona R. Kolbinger & Jakob Nikolas Kather
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Zusammenfassung:Technical metrics used to evaluate medical artificial intelligence tools often fail to predict their clinical impact. We characterize this discordance and propose a framework of study designs to guide the translational process for clinical artificial intelligence tools, acknowledging their diversity and specific validation requirements.
Beschreibung:Gesehen am 06.03.2026
Beschreibung:Online Resource
ISSN:2662-8457
DOI:10.1038/s43588-025-00901-x