An above-average lymph node yield removed during curative neck dissection in advanced head and neck squamous cell carcinomas improves survival
For appropriate treatment, lymph nodes must be removed in advanced squamous cell cancers of the head and neck in a procedure called neck dissection. The surgeon’s aim is to minimise surgical risk while achieving the best possible outcome, so the question of how many lymph nodes should be resected in...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
25 December 2025
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| In: |
Cancers
Year: 2025, Volume: 18, Issue: 1, Pages: 1-15 |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers18010068 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/cancers18010068 Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2072-6694/18/1/68 
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| Author Notes: | Miray-Su Yılmaz Topçuoğlu, Thiemo Seidler, Patrick J. Schuler, Christel Herold-Mende, Rolf Warta and Gerhard Dyckhoff |
| Summary: | For appropriate treatment, lymph nodes must be removed in advanced squamous cell cancers of the head and neck in a procedure called neck dissection. The surgeon’s aim is to minimise surgical risk while achieving the best possible outcome, so the question of how many lymph nodes should be resected in these cases to gain a long survival remains a topic of discussion. The patient data, surgery information, and outcome of a total of 234 patients with this type of cancer who were treated at a German university hospital between 1997 and 2018 were investigated. The study showed that a thorough neck dissection involving an above-average number of nodes can improve survival rates, especially when performed on the side opposite the primary tumour. |
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| Item Description: | Veröffentlicht: 25. Dezember 2025 Gesehen am 09.03.2026 |
| Physical Description: | Online Resource |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers18010068 |