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Repurposing PDE5-inhibitors: sildenafil drives arteriogenesis via localized regenerative inflammation

Arteriogenesis, the growth of pre-existing arterioles into functional collateral arteries, represents a key adaptive response to severe arterial steno...

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Main Authors: Elbs, Katharina (Author) , Bobrowski, Lisa (Author) , Arnholdt, Christoph (Author) , Kübler, Matthias (Author) , Götz, Philipp (Author) , Rohrmoser, Michael R. (Author) , Merkus, Daphne (Author) , Lasch, Manuel (Author) , Deindl, Elisabeth (Author)
Format: Article (Journal)
Language:English
Published: 19 January 2026
In: International journal of molecular sciences
Year: 2026, Volume: 27, Issue: 2, Pages: 1-19
ISSN:1422-0067
DOI:10.3390/ijms27020985
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/ijms27020985
Verlag, kostenfrei, Volltext: https://www.mdpi.com/1422-0067/27/2/985
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Author Notes:Katharina Elbs, Lisa Bobrowski, Christoph Arnholdt, Matthias Kübler, Philipp Götz, Michael R. Rohrmoser, Daphne Merkus, Manuel Lasch and Elisabeth Deindl
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Summary:Arteriogenesis, the growth of pre-existing arterioles into functional collateral arteries, represents a key adaptive response to severe arterial steno...
Item Description:Gesehen am 27.03.2026
Physical Description:Online Resource
ISSN:1422-0067
DOI:10.3390/ijms27020985

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