Deep learning model for breast shear wave elastography to improve breast cancer diagnosis (INSPiRED 006): an international, multicenter analysis
PURPOSE Shear wave elastography (SWE) has been investigated as a complement to B-mode ultrasound for breast cancer diagnosis. Although multicenter trials suggest benefits for patients with Breast Imaging Reporting and Data System (BI-RADS) 4(a) breast masses, widespread adoption remains limited becau...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
August 20, 2025
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| In: |
Journal of clinical oncology
Year: 2025, Volume: 43, Issue: 32, Pages: 3482-3493 |
| ISSN: | 1527-7755 |
| DOI: | 10.1200/JCO-24-02681 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1200/JCO-24-02681 Verlag, lizenzpflichtig, Volltext: https://ascopubs.org/doi/10.1200/JCO-24-02681 |
| Author Notes: | Lie Cai, André Pfob, Richard G. Barr, Volker Duda, Zaher Alwafai, Corinne Balleyguier, Dirk-André Clevert, Sarah Fastner, Christina Gomez, Manuela Goncalo, Ines Gruber, Markus Hahn, Panagiotis Kapetas, Juliane Nees, Ralf Ohlinger, Fabian Riedel, Matthieu Rutten, Anne Stieber, Riku Togawa, Chris Sidey-Gibbons, Mitsuhiro Tozaki, Sebastian Wojcinski, Joerg Heil, Michael Golatta |
| Summary: | PURPOSE Shear wave elastography (SWE) has been investigated as a complement to B-mode ultrasound for breast cancer diagnosis. Although multicenter trials suggest benefits for patients with Breast Imaging Reporting and Data System (BI-RADS) 4(a) breast masses, widespread adoption remains limited because of the absence of validated velocity thresholds. This study aims to develop and validate a deep learning (DL) model using SWE images (artificial intelligence [AI]-SWE) for BI-RADS 3 and 4 breast masses and compare its performance with human experts using B-mode ultrasound. |
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| Item Description: | Gesehen am 26.05.2026 Online veröffentlicht: 20. August 2025 |
| Physical Description: | Online Resource |
| ISSN: | 1527-7755 |
| DOI: | 10.1200/JCO-24-02681 |