Integrative multiomics and drug sensitivity profiling reveal potential biomarkers and therapeutic strategies in pediatric solid tumors

The combination of multiomics analysis and drug sensitivity profiling identified two signatures related to drug sensitivity in pediatric solid tumors, contributing to the advancement of functional precision medicine and personalized treatment strategies.This article is part of a special series: Driv...

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Main Authors:	ElHarouni, Dina (Author) , Hernansaiz Ballesteros, Rosa (Author) , Peterziel, Heike (Author) , Balasubramanian, Gnana Prakash (Author) , Previti, A. Christopher (Author) , Schramm, Kathrin (Author) , Blattner-Johnson, Mirjam (Author) , Kabbe, Rolf (Author) , Jones, Barbara Christine (Author) , Oppermann, Sina (Author) , Jones, David T. W. (Author) , Pfister, Stefan (Author) , Witt, Olaf (Author) , Sáez Rodríguez, Julio (Author) , Oehme, Ina (Author) , Jäger, Natalie (Author) , Schlesner, Matthias (Author)
Format:	Article (Journal)
Language:	English
Published:	1 February 2026
In:	Cancer research Year: 2026, Volume: 86, Issue: 3, Pages: 773-784
ISSN:	1538-7445
DOI:	10.1158/0008-5472.CAN-24-1938
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/0008-5472.CAN-24-1938
Author Notes:	Dina ElHarouni, Rosa Hernansaiz-Ballesteros, Heike Peterziel, Gnana Prakash Balasubramanian, Christopher Previti, Kathrin Schramm, Mirjam Blattner-Johnson, Rolf Kabbe, Barbara C. Jones, Sina Oppermann, David T.W. Jones, Stefan M. Pfister, Olaf Witt, Julio Saez-Rodriguez, Ina Oehme, Natalie Jäger, and Matthias Schlesner