Modelling lockdown and exit strategies for COVID-19 in Singapore

Background - With at least 94 countries undergoing or exiting lockdowns for contact suppression to control the COVID-19 outbreak, sustainable and public health-driven exit strategies are required. Here we explore the impact of lockdown and exit strategies in Singapore for immediate planning. - Metho...

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Main Authors: Dickens, Borame L. (Author) , Koo, Joel R. (Author) , Lim, Jue Tao (Author) , Park, Minah (Author) , Quaye, Sharon (Author) , Sun, Haoyang (Author) , Sun, Yinxiaohe (Author) , Pung, Rachael (Author) , Wilder-Smith, Annelies (Author) , Chai, Louis Yi Ann (Author) , Lee, Vernon (Author) , Cook, Alex R. (Author)
Format: Article (Journal)
Language:English
Published: August 2020
In: The lancet. Regional Health. Western Pacific
Year: 2020, Volume: 1, Pages: 1-7
ISSN:2666-6065
DOI:10.1016/j.lanwpc.2020.100004
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.lanwpc.2020.100004
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2666606520300043
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Author Notes:Borame L. Dickens, Joel R. Koo, Jue Tao Lim, Minah Park, Sharon Quaye, Haoyang Sun, Yinxiaohe Sun, Rachael Pung, Annelies Wilder-Smith, Louis Yi Ann Chai, Vernon J. Lee, Alex R. Cook
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Summary:Background - With at least 94 countries undergoing or exiting lockdowns for contact suppression to control the COVID-19 outbreak, sustainable and public health-driven exit strategies are required. Here we explore the impact of lockdown and exit strategies in Singapore for immediate planning. - Methods - We use an agent-based model to examine the impacts of epidemic control over 480 days. A limited control baseline of case isolation and household member quarantining is used. We measure the impact of lockdown duration and start date on final infection attack sizes. We then apply a 3-month gradual exit strategy, immediately re-opening schools and easing workplace distancing measures, and compare this to long-term social distancing measures. - Findings - At baseline, we estimated 815 400 total infections (21.6% of the population). Early lockdown at 5 weeks with no exit strategy averted 18 500 (2.27% of baseline averted), 21 300 (2.61%) and 22 400 (2.75%) infections for 6, 8 and 9-week lockdown durations. Using the exit strategy averted a corresponding 114 700, 121 700 and 126 000 total cases, representing 12.07-13.06% of the total epidemic size under baseline. This diminishes to 9 900-11 300 for a late 8-week start time. Long-term social distancing at 6 and 8-week durations are viable but less effective. - Interpretation - Gradual release exit strategies are critical to maintain epidemic suppression under a new normal. We present final infection attack sizes assuming the ongoing importation of cases, which require preparation for a potential second epidemic wave due to ongoing epidemics elsewhere. - Funding - Singapore Ministry of Health, Singapore Population Health Improvement Centre.
Item Description:Gesehen am 20.08.2026
Physical Description:Online Resource
ISSN:2666-6065
DOI:10.1016/j.lanwpc.2020.100004