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Imatinib mesylate (Glivec) inhibits Schwann cell viability and reduces the size of human plexiform neurofibroma in a xenograft model

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Plexiform neurofibromas (PNF), one of the major features of neurofibromatosis type 1 (NF1), are characterized by complex cellular composition and mostly slow but variable growth patterns. In this study, we examined the effect of imatinib mesylate, a receptor tyrosine kinase inhibitor, on PNF-derived...

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Other Authors: Demestre, Maria (Other) , Herzberg, Jan (Other) , Holtkamp, Nikola (Other) , Hagel, Christian (Other) , Reuss, David (Other) , Friedrich, Reinhard E. (Other) , Kluwe, Lan (Other) , Deimling, Andreas von (Other) , Mautner, Victor Felix (Other) , Kurtz, Andreas (Other)
Format: Article (Journal)
Language:English
Published: 2010
In: Journal of neuro-oncology
Year: 2010, Volume: 98, Issue: 1, Pages: 11-20
ISSN:0167-594X
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Author Notes:Maria Demestre, Jan Herzberg, Nikola Holtkamp, Christian Hagel, David Reuss, Reinhard E. Friedrich, Lan Kluwe, Andreas von Deimling, Victor-F. Mautner, Andreas Kurtz
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Imatinib mesylate (Glivec) inhibits Schwann cell viability and reduces the size of human plexiform neurofibroma in a xenograft model by Demestre, Maria (Author) , Herzberg, Jan (Author) , Holtkamp, Nikola (Author) , Hagel, Christian (Author) , Reuss, David (Author) , Friedrich, Reinhard E. (Author) , Kluwe, Lan (Author) , Deimling, Andreas von (Author) , Mautner, Victor Felix (Author) , Kurtz, Andreas (Author) ,


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