1,25-dihydroxyvitamin D3 inhibits corneal wound healing in an ex-vivo mouse model
Impaired healing of corneal injuries can result in ulceration and complete loss of vision, especially in the elderly. Such patients frequently also exhibit vitamin D insufficiency. 1,25-dihydroxyvitamin D3 is the active vitamin D metabolite. As it affects cell proliferation and inflammation, we here...
Gespeichert in:
| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
21 January 2016
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| In: |
Graefe's archive for clinical and experimental ophthalmology
Year: 2016, Jahrgang: 254, Heft: 4, Pages: 717-724 |
| ISSN: | 1435-702X |
| DOI: | 10.1007/s00417-016-3267-4 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00417-016-3267-4
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| Verfasserangaben: | Saadettin Sel, Stefanie Trau, Friedrich Paulsen, Thomas Kalinski, Gabriele I. Stangl, Norbert Nass |
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| 520 | |a Impaired healing of corneal injuries can result in ulceration and complete loss of vision, especially in the elderly. Such patients frequently also exhibit vitamin D insufficiency. 1,25-dihydroxyvitamin D3 is the active vitamin D metabolite. As it affects cell proliferation and inflammation, we herein aimed at elucidating its influence on corneal wound healing after alkali burn by using in vitro and ex vivo techniques. | ||
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