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P-glycoprotein (P-gp)
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A physiologically based pharmacokinetic model of ketoconazole and its metabolites as drug-drug interaction perpetrators
by Marok, Fatima (Author)
, Wojtyniak, Jan-Georg (Author)
, Fuhr, Laura Maria (Author)
, Selzer, Dominik (Author)
, Schwab, Matthias (Author)
, Weiß, Johanna (Author)
, Haefeli, Walter E. (Author)
, Lehr, Thorsten (Author)
,
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Pharmaceutics, 15 (2023), 2, Artikel-ID 679, Seite 1-22
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Fuhr, Laura Maria
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Haefeli, Walter E.
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cytochrome P450 3A4 (CYP3A4)
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drug-drug interaction
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drug-food interaction
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ketoconazole
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metabolites
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physiologically based pharmacokinetic (PBPK) modeling
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reversible inhibition
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