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The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial by Kilburn, Lindsay B. (Author) , Khuong-Quang, Dong-Anh (Author) , Hansford, Jordan R. (Author) , Landi, Daniel (Author) , van der Lugt, Jasper (Author) , Leary, Sarah E. S. (Author) , Driever, Pablo Hernáiz (Author) , Bailey, Simon (Author) , Perreault, Sébastien (Author) , McCowage, Geoffrey (Author) , Waanders, Angela J. (Author) , Ziegler, David S. (Author) , Witt, Olaf (Author) , Baxter, Patricia A. (Author) , Kang, Hyoung Jin (Author) , Hassall, Timothy E. (Author) , Han, Jung Woo (Author) , Hargrave, Darren R. (Author) , Franson, Andrea T. (Author) , Yalon Oren, Michal (Author) , Toledano, Helen (Author) , Larouche, Valérie (Author) , Kline, Cassie (Author) , Abdelbaki, Mohamed S. (Author) , Jabado, Nada (Author) , Gottardo, Nicholas G. (Author) , Gerber, Nicolas U. (Author) , Whipple, Nicholas S. (Author) , Segal, Devorah (Author) , Chi, Susan N. (Author) , Oren, Liat (Author) , Tan, Enrica E. K. (Author) , Müller, Sabine (Author) , Cornelio, Izzy (Author) , McLeod, Lisa (Author) , Zhao, Xin (Author) , Walter, Ashley (Author) , Da Costa, Daniel (Author) , Manley, Peter (Author) , Blackman, Samuel C. (Author) , Packer, Roger J. (Author) , Nysom, Karsten (Author) ,

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Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage by Ghasemi, David R. (Author) , Okonechnikov, Konstantin (Author) , Rademacher, Anne (Author) , Tirier, Stephan Marius (Author) , Maaß, Kendra K. (Author) , Schumacher, Hanna (Author) , Joshi, Piyush (Author) , Gold, Maxwell P. (Author) , Sundheimer, Julia (Author) , Statz, Britta (Author) , Rifaioglu, Ahmet (Author) , Bauer, Katharina (Author) , Schumacher, Sabrina (Author) , Bortolomeazzi, Michele (Author) , Giangaspero, Felice (Author) , Ernst, Kati (Author) , Clifford, Steven C. (Author) , Sáez Rodríguez, Julio (Author) , Jones, David T. W. (Author) , Kawauchi, Daisuke (Author) , Fraenkel, Ernest (Author) , Mallm, Jan-Philipp (Author) , Rippe, Karsten (Author) , Korshunov, Andrey (Author) , Pfister, Stefan (Author) , Pajtler, Kristian Wilfried (Author) ,

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Developmental basis of SHH medulloblastoma heterogeneity by Gold, Maxwell (Author) , Ong, Winnie (Author) , Masteller, Andrew M. (Author) , Ghasemi, David R. (Author) , Galindo, Julie Anne (Author) , Park, Noel R. (Author) , Huynh, Nhan C. (Author) , Donde, Aneesh (Author) , Pister, Veronika (Author) , Saurez, Raul A. (Author) , Vladoiu, Maria C. (Author) , Hwang, Grace H. (Author) , Eisemann, Tanja (Author) , Donovan, Laura K. (Author) , Walker, Adam D. (Author) , Benetatos, Joseph (Author) , Dufour, Christelle (Author) , Garzia, Livia (Author) , Segal, Rosalind A. (Author) , Wechsler-Reya, Robert J. (Author) , Mesirov, Jill P. (Author) , Korshunov, Andrey (Author) , Pajtler, Kristian Wilfried (Author) , Pomeroy, Scott L. (Author) , Ayrault, Olivier (Author) , Davidson, Shawn M. (Author) , Cotter, Jennifer A. (Author) , Taylor, Michael D. (Author) , Fraenkel, Ernest (Author) ,

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Clinical and molecular study of radiation-induced gliomas by Trkova, Katerina (Author) , Sumerauer, David (Author) , Bubenikova, Adela (Author) , Krskova, Lenka (Author) , Vicha, Ales (Author) , Koblizek, Miroslav (Author) , Zamecnik, Josef (Author) , Jurasek, Bruno (Author) , Kyncl, Martin (Author) , Malinova, Bela (Author) , Ondrova, Barbora (Author) , Jones, David T. W. (Author) , Sill, Martin (Author) , Strnadova, Martina (Author) , Stolova, Lucie (Author) , Misove, Adela (Author) , Benes, Vladimir (Author) , Zapotocky, Michal (Author) ,

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Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology by Sturm, Dominik (Author) , Capper, David (Author) , Andreiuolo, Felipe (Author) , Gessi, Marco (Author) , Kölsche, Christian (Author) , Reinhardt, Annekathrin (Author) , Sievers, Philipp (Author) , Wefers, Annika K. (Author) , Ebrahimi, Azadeh (Author) , Suwala, Abigail Kora (Author) , Gielen, Gerrit H. (Author) , Sill, Martin (Author) , Schrimpf, Daniel (Author) , Stichel, Damian (Author) , Hovestadt, Volker (Author) , Daenekas, Bjarne (Author) , Rode, Agata (Author) , Hamelmann, Stefan (Author) , Previti, A. Christopher (Author) , Jäger, Natalie (Author) , Buchhalter, Ivo (Author) , Blattner-Johnson, Mirjam (Author) , Jones, Barbara Christine (Author) , Warmuth-Metz, Monika (Author) , Bison, Brigitte (Author) , Grund, Kerstin (Author) , Sutter, Christian (Author) , Hirsch, Steffen (Author) , Dikow, Nicola (Author) , Witt, Olaf (Author) , Deimling, Andreas von (Author) , Müller, Hermann L. (Author) , Pietsch, Torsten (Author) , Sahm, Felix (Author) , Pfister, Stefan (Author) , Jones, David T. W. (Author) ,

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Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers by Thatikonda, Venu (Author) , Islam, S. M. Ashiqul (Author) , Autry, Robert J. (Author) , Jones, Barbara Christine (Author) , Gröbner, Susanne N. (Author) , Warsow, Gregor (Author) , Hutter, Barbara (Author) , Hübschmann, Daniel (Author) , Fröhling, Stefan (Author) , Kool, Marcel (Author) , Blattner-Johnson, Mirjam (Author) , Jones, David T. W. (Author) , Alexandrov, Ludmil B. (Author) , Pfister, Stefan (Author) , Jäger, Natalie (Author) ,

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MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas by Sigaud, Romain (Author) , Albert, Thomas K. (Author) , Hess, Caroline (Author) , Hielscher, Thomas (Author) , Winkler, Nadine (Author) , Kocher, Daniela (Author) , Walter, Carolin (Author) , Münter, Daniel (Author) , Selt, Florian (Author) , Usta, Diren (Author) , Ecker, Jonas (Author) , Brentrup, Angela (Author) , Hasselblatt, Martin (Author) , Thomas, Christian (Author) , Varghese, Julian (Author) , Capper, David (Author) , Thomale, Ulrich W. (Author) , Hernáiz Driever, Pablo (Author) , Simon, Michèle (Author) , Horn, Svea (Author) , Herz, Nina Annika (Author) , Koch, Arend (Author) , Sahm, Felix (Author) , Hamelmann, Stefan (Author) , Faria-Andrade, Augusto (Author) , Jabado, Nada (Author) , Schuhmann, Martin U. (Author) , Schouten-van Meeteren, Antoinette Y. N. (Author) , Hoving, Eelco (Author) , Brummer, Tilman (Author) , Tilburg, Cornelis M. van (Author) , Pfister, Stefan (Author) , Witt, Olaf (Author) , Jones, David T. W. (Author) , Kerl, Kornelius (Author) , Milde, Till (Author) ,

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MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis by Alborzinia, Hamed (Author) , Flórez, Andrés F. (Author) , Kreth, Sina (Author) , Brückner, Lena M. (Author) , Yildiz, Umut (Author) , Gartlgruber, Moritz (Author) , Odoni, Dorett (Author) , Poschet, Gernot (Author) , Garbowicz, Karolina (Author) , Shao, Chunxuan (Author) , Klein, Corinna (Author) , Meier, Jasmin (Author) , Zeisberger, Petra (Author) , Nadler-Holly, Michal (Author) , Ziehm, Matthias (Author) , Paul, Franziska (Author) , Burhenne, Jürgen (Author) , Bell, Emma (Author) , Shaikhkarami, Marjan (Author) , Würth, Roberto (Author) , Stainczyk, Sabine A. (Author) , Wecht, Elisa M. (Author) , Kreth, Jochen (Author) , Büttner, Michael (Author) , Ishaque, Naveed (Author) , Schlesner, Matthias (Author) , Nicke, Barbara (Author) , Stresemann, Carlo (Author) , Llamazares-Prada, Maria (Author) , Reiling, Jan H. (Author) , Fischer, Matthias (Author) , Amit, Ido (Author) , Selbach, Matthias (Author) , Herrmann, Carl (Author) , Wölfl, Stefan (Author) , Henrich, Kai-Oliver (Author) , Höfer, Thomas (Author) , Trumpp, Andreas (Author) , Westermann, Frank (Author) ,

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EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma by Völtzke, Kai Philipp (Author) , Scharov, Katerina (Author) , Funk, Cornelius M. (Author) , Kahler, Alisa (Author) , Picard, Daniel (Author) , Hruby, Laura (Author) , Orth, Martin Franz (Author) , Remke, Marc (Author) , Esposito, Irene (Author) , Kirchner, Thomas (Author) , Schramm, Alexander (Author) , Rotblat, Barak (Author) , Grünewald, Thomas G. P. (Author) , Reifenberger, Guido (Author) , Leprivier, Gabriel (Author) ,

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Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM by Peterziel, Heike (Author) , Jamaladdin, Nora (Author) , ElHarouni, Dina (Author) , Gerloff, Xenia F. (Author) , Herter, Sonja (Author) , Fiesel, Petra (Author) , Berker, Yannick (Author) , Blattner-Johnson, Mirjam (Author) , Schramm, Kathrin (Author) , Jones, Barbara Christine (Author) , Reuss, David (Author) , Turunen, Laura (Author) , Friedenauer, Aileen (Author) , Holland-Letz, Tim (Author) , Sill, Martin (Author) , Weiser, Lena (Author) , Previti, A. Christopher (Author) , Balasubramanian, Gnanaprakash (Author) , Gerber, Nicolas U. (Author) , Gojo, Johannes (Author) , Hutter, Caroline (Author) , Øra, Ingrid (Author) , Lohi, Olli (Author) , Kattamis, Antonis (Author) , de Wilde, Bram (Author) , Westermann, Frank (Author) , Tippelt, Stephan (Author) , Graf, Norbert (Author) , Nathrath, Michaela (Author) , Sparber-Sauer, Monika (Author) , Sehested, Astrid (Author) , Kramm, Christof M. (Author) , Dirksen, Uta (Author) , Kallioniemi, Olli (Author) , Pfister, Stefan (Author) , Tilburg, Cornelis M. van (Author) , Jones, David T. W. (Author) , Saarela, Jani (Author) , Pietiäinen, Vilja (Author) , Jäger, Natalie (Author) , Schlesner, Matthias (Author) , Kopp-Schneider, Annette (Author) , Oppermann, Sina (Author) , Milde, Till (Author) , Witt, Olaf (Author) , Oehme, Ina (Author) ,

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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors by Bartl, Jasmin (Author) , Zanini, Marco (Author) , Bernardi, Flavia (Author) , Forget, Antoine (Author) , Blümel, Lena (Author) , Talbot, Julie (Author) , Picard, Daniel (Author) , Qin, Nan (Author) , Cancila, Gabriele (Author) , Gao, Qingsong (Author) , Nath, Soumav (Author) , Koumba, Idriss Mahoungou (Author) , Wolter, Marietta (Author) , Kuonen, François (Author) , Langini, Maike (Author) , Beez, Thomas (Author) , Munoz, Christopher (Author) , Pauck, David (Author) , Marquardt, Viktoria (Author) , Yu, Hua (Author) , Souphron, Judith (Author) , Korsch, Mascha (Author) , Mölders, Christina (Author) , Berger, Daniel (Author) , Göbbels, Sarah (Author) , Meyer, Frauke-Dorothee (Author) , Scheffler, Björn (Author) , Rotblat, Barak (Author) , Diederichs, Sven (Author) , Ramaswamy, Vijay (Author) , Suzuki, Hiromishi (Author) , Oro, Anthony (Author) , Stühler, Kai (Author) , Stefanski, Anja (Author) , Fischer, Ute (Author) , Leprivier, Gabriel (Author) , Willbold, Dieter (Author) , Steger, Gerhard (Author) , Büll, Alexander Kai (Author) , Kool, Marcel (Author) , Lichter, Peter (Author) , Pfister, Stefan (Author) , Northcott, Paul A. (Author) , Taylor, Michael D. (Author) , Borkhardt, Arndt (Author) , Reifenberger, Guido (Author) , Ayrault, Olivier (Author) , Remke, Marc (Author) ,

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The current landscape of immunotherapy for pediatric brain tumors by Hwang, Eugene (Author) , Sayour, Elias J. (Author) , Flores, Catherine T. (Author) , Grant, Gerald (Author) , Wechsler-Reya, Robert (Author) , Hoang-Minh, Lan B. (Author) , Kieran, Mark W. (Author) , Salcido, Joanne (Author) , Prins, Robert M. (Author) , Figg, John W. (Author) , Platten, Michael (Author) , Candelario, Kate M. (Author) , Hale, Paul G. (Author) , Blatt, Jason E. (Author) , Governale, Lance S. (Author) , Okada, Hideho (Author) , Mitchell, Duane A. (Author) , Pollack, Ian F. (Author) ,

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A systematic analysis of genetic interactions and their underlying biology in childhood cancer by Daub, Joséphine (Author) , Amini, Saman (Author) , Kersjes, Denise J. E. (Author) , Ma, Xiaotu (Author) , Jäger, Natalie (Author) , Zhang, Jinghui (Author) , Pfister, Stefan (Author) , Holstege, Frank Charles Patrick (Author) , Kemmeren, Patrick (Author) ,

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Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury by Williamson, Laura M. (Author) , Rive, Craig M. (Author) , Di Francesco, Daniela (Author) , Titmuss, Emma (Author) , Chun, Hye-Jung E. (Author) , Brown, Scott D. (Author) , Milne, Katy (Author) , Pleasance, Erin (Author) , Lee, Anna F. (Author) , Yip, Stephen (Author) , Rosenbaum, Daniel G. (Author) , Hasselblatt, Martin (Author) , Johann, Pascal-David (Author) , Kool, Marcel (Author) , Harvey, Melissa (Author) , Dix, David (Author) , Renouf, Daniel J. (Author) , Holt, Robert A. (Author) , Nelson, Brad H. (Author) , Hirst, Martin (Author) , Jones, Steven J. M. (Author) , Laskin, Janessa (Author) , Rassekh, Shahrad R. (Author) , Deyell, Rebecca J. (Author) , Marra, Marco A. (Author) ,

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Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms by Bauer, Julia (Author) , Cuvelier, Nicole (Author) , Ragab, Nada (Author) , Simon-Keller, Katja (Author) , Nitzki, Frauke (Author) , Geyer, Natalie (Author) , Botermann, Dominik S. (Author) , Elmer, Dominik P. (Author) , Rosenberger, Albert (Author) , Rando, Thomas A. (Author) , Biressi, Stefano (Author) , Fagin, James A. (Author) , Saur, Dieter (Author) , Dullin, Christian (Author) , Schildhaus, Hans-Ulrich (Author) , Schulz-Schaeffer, Walter (Author) , Aberger, Fritz (Author) , Uhmann, Anja (Author) , Hahn, Heidi (Author) ,

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