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complement-dependent cytotoxicity
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Complement C5b-9 and cancer: mechanisms of cell damage, cancer counteractions, and approaches for intervention
by Fishelson, Zvi (Author)
, Kirschfink, Michael (Author)
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Frontiers in immunology, 10 (2019) Artikel-Nummer 752, 16 Seiten
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Neutralization of membrane complement regulators improves complement-dependent effector functions of therapeutic anticancer antibodies targeting leukemic cells
by Mamidi, Srinivas (Author)
, Höne, Simon (Author)
, Teufel, Claudia (Author)
, Sellner, Leopold (Author)
, Zenz, Thorsten (Author)
, Kirschfink, Michael (Author)
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OncoImmunology, 4 (2015), 3
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Medizinische Fakultät Heidelberg
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Klinikum der Universität Heidelberg
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Zentrum für Innere Medizin (Krehl Klinik)
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Institut für Immunologie und Serologie
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Kirschfink, Michael
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Fishelson, Zvi
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Höne, Simon
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Mamidi, Srinivas
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Sellner, Leopold
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Teufel, Claudia
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Zenz, Thorsten
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Medicine
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complement-dependent cytotoxicity
ADCC, antibody-dependent cellular cytotoxicity
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ALM, Alemtuzumab
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C5b-9
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CDC, complement-dependent cytotoxicity
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CDCC, complement-dependent cellular cytotoxicity
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MAC, membrane attack complex
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NHS, Normal Human Serum
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OFA, Ofatumumab
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PBLs, peripheral blood leukocytes
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RTX, Rituximab
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TRX, Trastuzumab
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alemtuzumab
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cancer immune resistance
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chronic lymphocytic leukemia
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complement
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complement regulatory proteins
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mCRP, membrane-bound complement regulatory protein
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ofatumumab
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opsonization
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regulated necrosis
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rituximab
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siRNA, small interfering RNA
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