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Inhibition of phosphodiesterase 10A by MP-10 rescues behavioral deficits and normalizes microglial morphology and synaptic pruning in a mouse model of FOXP1 syndrome
by Fröhlich, Henning (Author)
, Wang, Jing (Author)
, Althammer, Ferdinand (Author)
, Schubert, Tim (Author)
, Kluck, Nina (Author)
, Grinevich, Valéry (Author)
, Schmitteckert, Stefanie (Author)
, Schaaf, Christian P. (Author)
, Rappold, Gudrun (Author)
,
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Advanced science, (2025), Artikel-ID e00623, Seite 1-16
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Medizinische Fakultät Mannheim
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Althammer, Ferdinand
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Fröhlich, Henning
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Grinevich, Valéry
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Kluck, Nina
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Rappold, Gudrun
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Schaaf, Christian P.
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Schmitteckert, Stefanie
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Schubert, Tim
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Wang, Jing
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Psychology
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FOXP1 syndrome
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MP-10 (PF-2545920)
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Pde10a
mouse model
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treatment
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