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cyclophilin
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Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication
by Dujardin, Marie (Author)
, Madan Renes, Vanesa (Author)
, Gandhi, Neha S. (Author)
, Cantrelle, François-Xavier (Author)
, Launay, Hélène (Author)
, Huvent, Isabelle (Author)
, Bartenschlager, Ralf (Author)
, Lippens, Guy (Author)
, Hanoulle, Xavier (Author)
,
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The journal of biological chemistry, 294 (2019), 35, Seite 13171-13185
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Verlag, lizenzpflichtig, Volltext
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Klinikum der Universität Heidelberg
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Department für Infektiologie
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Bartenschlager, Ralf
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Cantrelle, François-Xavier
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Dujardin, Marie
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Gandhi, Neha S.
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Hanoulle, Xavier
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Huvent, Isabelle
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Launay, Hélène
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Lippens, Guy
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Madan Renes, Vanesa
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Chemistry
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RNA replication
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allosteric regulation
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conformer ensemble
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cyclophilin
hepatitis C virus (HCV)
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intrinsically disordered protein
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nonstructural protein 5A (NS5A)
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nuclear magnetic resonance (NMR)
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prolyl isomerase
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