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IgM cleavage by Streptococcus suis reduces IgM bound to the bacterial surface and is a novel complement evasion mechanism
by Rungelrath, Viktoria Charlotte (Author)
, Kirschfink, Michael (Author)
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Virulence, 9 (2018), 1, Seite 1314-1337
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Neutralization of membrane complement regulators improves complement-dependent effector functions of therapeutic anticancer antibodies targeting leukemic cells
by Mamidi, Srinivas (Author)
, Höne, Simon (Author)
, Teufel, Claudia (Author)
, Sellner, Leopold (Author)
, Zenz, Thorsten (Author)
, Kirschfink, Michael (Author)
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OncoImmunology, 4 (2015), 3
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Unconventional apoptosis of polymorphonuclear neutrophils (PMN): staurosporine delays exposure of phosphatidylserine and prevents phagocytosis by M[phi]-2 macrophages of PMN
by Franz, Sandra (Author)
, Muñoz Becerra, Luis Enrique (Author)
, Heyder, Petra (Author)
, Herrmann, Martin (Author)
, Schiller, Martin (Author)
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Clinical & experimental immunology, 179 (2015), 1, Seite 75-84
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Klinikum der Universität Heidelberg
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Zentrum für Innere Medizin (Krehl Klinik)
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Institut für Immunologie und Serologie
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Medizinische Fakultät Heidelberg
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Kirschfink, Michael
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Franz, Sandra
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Herrmann, Martin
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Heyder, Petra
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Höne, Simon
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Mamidi, Srinivas
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Muñoz Becerra, Luis Enrique
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Rungelrath, Viktoria Charlotte
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Schiller, Martin
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Sellner, Leopold
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Teufel, Claudia
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Zenz, Thorsten
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Topic
opsonization
ADCC, antibody-dependent cellular cytotoxicity
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ALM, Alemtuzumab
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CDC, complement-dependent cytotoxicity
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CDCC, complement-dependent cellular cytotoxicity
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IdeS-family protease
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IdeSsuis
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IgM
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MAC, membrane attack complex
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NHS, Normal Human Serum
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OFA, Ofatumumab
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PBLs, peripheral blood leukocytes
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PMN
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RTX, Rituximab
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Streptococcus suis
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TRX, Trastuzumab
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alemtuzumab
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apoptosis
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chronic lymphocytic leukemia
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clearance
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complement regulatory proteins
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complement-dependent cytotoxicity
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cysteine protease
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mCRP, membrane-bound complement regulatory protein
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ofatumumab
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rituximab
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siRNA, small interfering RNA
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staurosporine
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