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Horst Bickel

Horst Bickel Horst Bickel (28 June 1918 – 1 December 2000) was a German medical doctor.

With Guido Fanconi, he characterized Glycogen storage disease type XI in 1949.

He was also involved in the development of treatments for phenylketonuria. In 1951, Bickel, Evelyn Hickmans and John Gerrard were persuaded by a persistent mother to help her daughter, Sheila, who was suffering from phenylketonuria. They created a diet that was low in phenylalanine and the daughter's condition improved.

Despite Bickel’s contribution, his decision to discontinue Shiela’s treatment (even after knowing its effectiveness) caused her condition to worsen so much that she was moved out of her home into an institution for the rest of her life.

Bickel, Gerrard and Hickmans were awarded the John Scott Medal in 1962 for their discovery.

His birthday, 28 June, which he shares with Robert Guthrie, another important person for Phenylketonuria was taken up by the European Society for Phenylketonuria and Allied Disorders Treated as Phenylketonuria to launch the International PKU Day. Provided by Wikipedia
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    Overweight, obesity, and depression in multimorbid older adults: prevalence, diagnostic agreement, and associated factors in primary care : results from a multicenter observational... by Bludau, Daniel Christopher (Author) , Pabst, Alexander (Author) , Bleck, Franziska (Author) , Weyerer, Siegfried (Author) , Maier, Wolfgang (Author) , Gensichen, Jochen (Author) , Mergenthal, Karola (Author) , Bickel, Horst (Author) , Fuchs, Angela (Author) , Schäfer, Ingmar (Author) , König, Hans-Helmut (Author) , Wiese, Birgitt (Author) , Schön, Gerhard (Author) , Wegscheider, Karl (Author) , Scherer, Martin (Author) , Riedel-Heller, Steffi G. (Author) , Löbner, Margrit (Author) ,


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    Prognostic value of Alzheimer's disease plasma biomarkers in the oldest-old: a prospective primary care-based study by Adami, Pamela V. Martino (Author) , Chatterjee, Madhurima (Author) , Kleineidam, Luca (Author) , Weyerer, Siegfried (Author) , Bickel, Horst (Author) , Wiese, Birgitt (Author) , Riedel-Heller, Steffi G. (Author) , Scherer, Martin (Author) , Blennow, Kaj (Author) , Zetterberg, Henrik (Author) , Wagner, Michael (Author) , Schneider, Anja (Author) , Ramirez, Alfredo (Author) ,


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    Validation of MyFORTA: an automated tool to improve medications in older people based on the FORTA list by Wehling, Martin (Author) , Weindrich, Johannes (Author) , Weiß, Christel (Author) , Heser, Kathrin (Author) , Pabst, Alexander (Author) , Luppa, Melanie (Author) , Bickel, Horst (Author) , Weyerer, Siegfried (Author) , Pentzek, Michael (Author) , König, Hans-Helmut (Author) , Lühmann, Dagmar (Author) , van der Leeden, Carolin (Author) , Scherer, Martin (Author) , Riedel-Heller, Steffi G. (Author) , Wagner, Michael (Author) , Pazan, Farhad (Author) ,


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    Profiles of met and unmet care needs in the oldest old primary care patients with cognitive disorders and dementia: results of the AgeCoDe and AgeQualiDe study by Kraake, Sophia (Author) , Pabst, Alexander (Author) , Bickel, Horst (Author) , Pentzek, Michael (Author) , Fuchs, Angela (Author) , Wiese, Birgitt (Author) , Oey, Anke (Author) , König, Hans-Helmut (Author) , Brettschneider, Christian (Author) , Scherer, Martin (Author) , Mallon, Tina (Author) , Lühmann, Dagmar (Author) , Maier, Wolfgang (Author) , Wagner, Michael (Author) , Heser, Kathrin (Author) , Weyerer, Siegfried (Author) , Werle, Jochen (Author) , Riedel-Heller, Steffi G. (Author) , Stein, Janine (Author) ,


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    Alzheimer’s disease-specific transcriptomic and epigenomic changes in the tryptophan catabolic pathway by Choe, Kyonghwan (Author) , Ali, Muhammad (Author) , Lardenoije, Roy (Author) , Riemens, Renzo J. M. (Author) , Pishva, Ehsan (Author) , Bickel, Horst (Author) , Weyerer, Siegfried (Author) , Hoffmann, Per (Author) , Pentzek, Michael (Author) , Riedel-Heller, Steffi (Author) , Wiese, Birgitt (Author) , Scherer, Martin (Author) , Wagner, Michael (Author) , Mastroeni, Diego (Author) , Coleman, Paul D. (Author) , Ramirez, Alfredo (Author) , Ramakers, Inez H. G. B. (Author) , Verhey, Frans R. J. (Author) , Rutten, Bart P. F. (Author) , Kenis, Gunter (Author) , van den Hove, Daniel L. A. (Author) ,


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    An investigation into the relationship of circulating gut microbiome molecules and inflammatory markers with the risk of incident dementia in later life by Oluwagbemigun, Kolade Oluseye (Author) , Anesi, Andrea (Author) , Vrhovsek, Urska (Author) , Mattivi, Fulvio (Author) , Martino Adami, Pamela (Author) , Pentzek, Michael (Author) , Scherer, Martin (Author) , Riedel-Heller, Steffi G. (Author) , Weyerer, Siegfried (Author) , Bickel, Horst (Author) , Wiese, Birgitt (Author) , Schmid, Matthias (Author) , Cryan, John F. (Author) , Ramirez, Alfredo (Author) , Wagner, Michael (Author) , Nöthlings, Ute (Author) ,


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    Family history of dementia in old-age participants with subjective memory complaints predicts own risk for dementia in a longitudinal multi-center cohort study by Heser, Kathrin (Author) , Kleineidam, Luca (Author) , Wagner, Michael (Author) , Luppa, Melanie (Author) , Löbner, Margrit (Author) , Wiese, Birgitt (Author) , Oey, Anke (Author) , König, Hans-Helmut (Author) , Brettschneider, Christian (Author) , van der Leeden, Carolin (Author) , van den Bussche, Hendrik (Author) , Fuchs, Angela (Author) , Pentzek, Michael (Author) , Weyerer, Siegfried (Author) , Werle, Jochen (Author) , Bickel, Horst (Author) , Scherer, Martin (Author) , Maier, Wolfgang (Author) , Ramirez, Alfredo (Author) , Riedel-Heller, Steffi Gerlinde (Author) ,


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    Social isolation in the oldest-old: determinants and the differential role of family and friends by Moormann, Katharina Isabelle (Author) , Pabst, Alexander (Author) , Bleck, Franziska (Author) , Löbner, Margrit (Author) , Kaduszkiewicz, Hanna (Author) , van der Leeden, Carolin (Author) , Hajek, André (Author) , Brettschneider, Christian (Author) , Heser, Kathrin (Author) , Kleineidam, Luca (Author) , Werle, Jochen (Author) , Fuchs, Angela (Author) , Weeg, Dagmar (Author) , Bickel, Horst (Author) , Pentzek, Michael (Author) , Weyerer, Siegfried (Author) , Wiese, Birgitt (Author) , Wagner, Michael (Author) , Maier, Wolfgang (Author) , Scherer, Martin (Author) , König, Hans-Helmut (Author) , Riedel-Heller, Steffi Gerlinde (Author) ,


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    Disentangling the relationship of subjective cognitive decline and depressive symptoms in the development of cognitive decline and dementia: alternate format research article by Kleineidam, Luca (Author) , Wagner, Michael (Author) , Guski, Jannis (Author) , Wolfsgruber, Steffen (Author) , Miebach, Lisa (Author) , Bickel, Horst (Author) , König, Hans-Helmut (Author) , Weyerer, Siegfried (Author) , Lühmann, Dagmar (Author) , Kaduszkiewicz, Hanna (Author) , Luppa, Melanie (Author) , Röhr, Susanne (Author) , Pentzek, Michael (Author) , Wiese, Birgitt (Author) , Maier, Wolfgang (Author) , Scherer, Martin (Author) , Kornhuber, Johannes (Author) , Peters, Oliver (Author) , Frölich, Lutz (Author) , Wiltfang, Jens (Author) , Lewczuk, Piotr (Author) , Hüll, Michael (Author) , Ramirez, Alfredo (Author) , Jessen, Frank (Author) , Riedel-Heller, Steffi Gerlinde (Author) , Heser, Kathrin (Author) ,


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  10. 10
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    Low serum vitamin D status is associated with incident Alzheimer’s dementia in the oldest old by Melo van Lent, Debora (Author) , Egert, Sarah (Author) , Wolfsgruber, Steffen (Author) , Kleineidam, Luca (Author) , Weinhold, Leonie (Author) , Wagner-Thelen, Holger (Author) , Stoffel-Wagner, Birgit (Author) , Bickel, Horst (Author) , Wiese, Birgitt (Author) , Weyerer, Siegfried (Author) , Pentzek, Michael (Author) , Jessen, Frank (Author) , Schmid, Matthias (Author) , Maier, Wolfgang (Author) , Scherer, Martin (Author) , Riedel-Heller, Steffi G. (Author) , Ramirez, Alfredo (Author) , Wagner, Michael (Author) ,


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    Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve by Kleineidam, Luca (Author) , Wolfsgruber, Steffen (Author) , Weyrauch, Anne-Sophie (Author) , Zulka, Linn (Author) , Forstmeier, Simon (Author) , Roeske, Sandra (Author) , Bussche, Hendrik van den (Author) , Kaduszkiewicz, Hanna (Author) , Wiese, Birgitt (Author) , Weyerer, Siegfried (Author) , Werle, Jochen (Author) , Fuchs, Angela (Author) , Pentzek, Michael (Author) , Brettschneider, Christian (Author) , König, Hans-Helmut (Author) , Weeg, Dagmar (Author) , Bickel, Horst (Author) , Luppa, Melanie (Author) , Rodriguez, Francisca S. (Author) , Freiesleben, Silka Dawn (Author) , Erdogan, Selin (Author) , Unterfeld, Chantal (Author) , Peters, Oliver Hubertus (Author) , Spruth, Eike Jakob (Author) , Altenstein, Slawek (Author) , Lohse, Andrea (Author) , Priller, Josef (Author) , Fliessbach, Klaus (Author) , Kobeleva, Xenia Vladimirovna (Author) , Schneider, Anja (Author) , Bartels, Claudia (Author) , Schott, Björn H. (Author) , Wiltfang, Jens (Author) , Maier, Franziska (Author) , Glanz, Wenzel (Author) , Incesoy, Enise I. (Author) , Butryn, Michaela (Author) , Düzel, Emrah (Author) , Buerger, Katharina (Author) , Janowitz, Daniel (Author) , Ewers, Michael (Author) , Rauchmann, Boris-Stephan (Author) , Perneczky, Robert (Author) , Kilimann, Ingo (Author) , Görß, Doreen (Author) , Teipel, Stefan (Author) , Laske, Christoph (Author) , Munk, Matthias Hans Joachim (Author) , Spottke, Annika (Author) , Roy, Nina (Author) , Brosseron, Frederic (Author) , Heneka, Michael Thomas (Author) , Ramírez, Alfredo (Author) , Yakupov, Renat (Author) , Scherer, Martin (Author) , Maier, Wolfgang (Author) , Jessen, Frank (Author) , Riedel-Heller, Steffi Gerlinde (Author) , Wagner, Michael (Author) ,


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  12. 12
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    Higher FORTA (Fit fOR The Aged) scores are associated with poor functional outcomes, dementia, and mortality in older people: pharmacoepidemiology and prescreption by Pazan, Farhad (Author) , Breunig, Hanna (Author) , Weiß, Christel (Author) , Röhr, Susanne (Author) , Luppa, Melanie (Author) , Pentzek, Michael (Author) , Bickel, Horst (Author) , Weeg, Dagmar (Author) , Weyerer, Siegfried (Author) , Wiese, Birgitt (Author) , König, Hans-Helmut (Author) , Brettschneider, Christian (Author) , Heser, Kathrin (Author) , Maier, Wolfgang (Author) , Scherer, Martin (Author) , Riedel-Heller, Steffi Gerlinde (Author) , Wagner, Michael (Author) , Wehling, Martin (Author) ,


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  13. 13
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    Social isolation and incident dementia in the oldest-old: a competing risk analysis by Grothe, Jessica (Author) , Röhr, Susanne (Author) , Luppa, Melanie (Author) , Pabst, Alexander (Author) , Kleineidam, Luca (Author) , Heser, Kathrin (Author) , Fuchs, Angela (Author) , Pentzek, Michael (Author) , Oey, Anke (Author) , Wiese, Birgitt (Author) , Lühmann, Dagmar (Author) , van den Bussche, Hendrik (Author) , Weyerer, Siegfried (Author) , Werle, Jochen (Author) , Weeg, Dagmar (Author) , Bickel, Horst (Author) , Scherer, Martin (Author) , König, Hans-Helmut (Author) , Hajek, André (Author) , Wagner, Michael (Author) , Riedel-Heller, Steffi G. (Author) ,


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  14. 14
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    Effects of APOE e4-allele and mental work demands on cognitive decline in old age: Results from the German Study on Ageing, Cognition, and Dementia in primary care patients (AgeCoD... by Rodriguez, Francisca S. (Author) , Röhr, Susanne (Author) , Pabst, Alexander (Author) , Kleineidam, Luca (Author) , Fuchs, Angela (Author) , Wiese, Birgitt (Author) , Lühmann, Dagmar (Author) , Brettschneider, Christian (Author) , Wolfsgruber, Steffen (Author) , Pentzek, Michael (Author) , Bussche, Hendrik van den (Author) , König, Hans-Helmut (Author) , Weyerer, Siegfried (Author) , Werle, Jochen (Author) , Bickel, Horst (Author) , Weeg, Dagmar (Author) , Maier, Wolfgang (Author) , Scherer, Martin (Author) , Wagner, Michael (Author) , Riedel-Heller, Steffi Gerlinde (Author) ,


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  15. 15
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    Non-random relations in drug use expressed as patterns comprising prescription and over-the-counter drugs in multimorbid elderly patients in primary care: Data of the exploratory a... by Krüger, Caroline (Author) , Schäfer, Ingmar (Author) , Bussche, Hendrik van den (Author) , Baehr, Michael (Author) , Bickel, Horst (Author) , Fuchs, Angela (Author) , Gensichen, Jochen (Author) , Maier, Wolfgang (Author) , Riedel-Heller, Steffi Gerlinde (Author) , König, Hans-Helmut (Author) , Dahlhaus, Anne (Author) , Schön, Gerhard (Author) , Weyerer, Siegfried (Author) , Wiese, Birgitt (Author) , Renteln-Kruse, Wolfgang von (Author) , Langebrake, Claudia (Author) , Scherer, Martin (Author) ,


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  16. 16
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    Associations and correlates of general versus specific successful ageing components by Thoma, Myriam Verena (Author) , Kleineidam, Luca (Author) , Forstmeier, Simon (Author) , Maercker, Andreas (Author) , Weyerer, Siegfried (Author) , Eisele, Marion (Author) , Bussche, Hendrik van den (Author) , König, Hans-Helmut (Author) , Röhr, Susanne (Author) , Stein, Janine (Author) , Wiese, Birgitt (Author) , Pentzek, Michael (Author) , Bickel, Horst (Author) , Maier, Wolfgang (Author) , Scherer, Martin (Author) , Riedel-Heller, Steffi G. (Author) , Wagner, Michael (Author) ,


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  17. 17
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    Prevalence and factors associated with obesity among the oldest old by Hajek, André (Author) , Brettschneider, Christian (Author) , van der Leeden, Carolin (Author) , Luehmann, Dagmar (Author) , Oey, Anke (Author) , Wiese, Birgitt (Author) , Weyerer, Siegfried (Author) , Werle, Jochen (Author) , Fuchs, Angela (Author) , Pentzek, Michael (Author) , Röhr, Susanne (Author) , Löbner, Margrit (Author) , Mösch, Edelgard (Author) , Bickel, Horst (Author) , Heser, Kathrin (Author) , Wagner, Michael (Author) , Scherer, Martin (Author) , Maier, Wolfgang (Author) , Riedel-Heller, Steffi G. (Author) , König, Hans-Helmut (Author) ,


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  18. 18
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    Prediction of dementia of Alzheimer type by different types of subjective cognitive decline by Jessen, Frank (Author) , Kleineidam, Luca (Author) , Wolfsgruber, Steffen (Author) , Bickel, Horst (Author) , Brettschneider, Christian (Author) , Fuchs, Angela (Author) , Kaduszkiewicz, Hanna (Author) , König, Hans-Helmut (Author) , Mallon, Tina (Author) , Mamone, Silke (Author) , Pabst, Alexander (Author) , Pentzek, Michael (Author) , Roehr, Susanne (Author) , Weeg, Dagmar (Author) , Jochen, Werle (Author) , Weyerer, Siegfried (Author) , Wiese, Birgitt (Author) , Maier, Wolfgang (Author) , Scherer, Martin (Author) , Riedel-Heller, Steffi (Author) , Wagner, Michael (Author) ,


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    Prevalence and determinants of driving habits in the oldest old: Results of the multicenter prospective AgeCoDe-AgeQualiDe study by Hajek, André (Author) , Brettschneider, Christian (Author) , Eisele, Marion (Author) , van den Bussche, Hendrik (Author) , Wiese, Birgitt (Author) , Mamone, Silke (Author) , Weyerer, Siegfried (Author) , Werle, Jochen (Author) , Leve, Verena (Author) , Pentzek, Michael (Author) , Röhr, Susanne (Author) , Stein, Janine (Author) , Bickel, Horst (Author) , Mösch, Edelgard (Author) , Heser, Kathrin (Author) , Wagner, Michael (Author) , Scherer, Martin (Author) , Maier, Wolfgang (Author) , Riedel-Heller, Steffi G. (Author) , König, Hans-Helmut (Author) ,


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  20. 20
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    Determinants of health-care costs in the oldest-old in Germany by Brettschneider, Christian (Author) , Hajek, Andre (Author) , Röhr, Susanne (Author) , Fuchs, Angela (Author) , Weeg, Dagmar (Author) , Mamone, Silke (Author) , Werle, Jochen (Author) , Heser, Kathrin (Author) , Mallon, Tina (Author) , Stein, Janine (Author) , Pentzek, Michael (Author) , Bickel, Horst (Author) , Wiese, Birgitt (Author) , Weyerer, Siegfried (Author) , Wagner, Michael (Author) , Bussche, Hendrik van den (Author) , Maier, Wolfgang (Author) , Scherer, Martin (Author) , Riedel-Heller, Steffi G (Author) , König, Hans-Helmut (Author) ,


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