Intravoxel incoherent motion (IVIM) MRI: principles and applications
Cover -- Half Title -- Title -- Copyrights -- Dedication -- Contents -- Foreword -- Preface -- Section I Introduction to IVIM MRI -- Chapter 1. Introduction to IVIM MRI Denis Le Bihan -- 1.1 The IVIM Concept -- 1.1.1 Molecular Diffusion -- 1.1.2 Perfusion-Driven Pseudodiffusion -- 1.1.3 Other Source...
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| Other Authors: | , , |
| Format: | Book/Monograph |
| Language: | English |
| Published: |
Milton
Pan Stanford Publishing
2018
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| Volumes / Articles: | Show Volumes / Articles. |
| Subjects: | |
| Online Access: | Aggregator, lizenzpflichtig, Volltext: https://ebookcentral.proquest.com/lib/kxp/detail.action?docID=5572472
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| Author Notes: | edited by Denis Le Bihan, Mami Iima, Christian Federau, Eric E. Sigmund |
| Summary: | Cover -- Half Title -- Title -- Copyrights -- Dedication -- Contents -- Foreword -- Preface -- Section I Introduction to IVIM MRI -- Chapter 1. Introduction to IVIM MRI Denis Le Bihan -- 1.1 The IVIM Concept -- 1.1.1 Molecular Diffusion -- 1.1.2 Perfusion-Driven Pseudodiffusion -- 1.1.3 Other Sources of IVIM -- 1.2 IVIM MRI -- 1.2.1 IVIM Contribution to the MRI Signal -- 1.2.2 Extracting Diffusion and Perfusion Parameters -- 1.3 Pitfalls to Consider for an Accurate Estimation of Perfusion-Driven IVIM Parameters -- 1.3.1 Non-Gaussian Tissue Diffusion -- 1.3.2 Rician Noise -- 1.3.3 Erratic Signals -- 1.4 Perfusion-Driven IVIM MRI and "Classical" Perfusion -- 1.4.1 IVIM MRI Reflects Capillary Network Architecture and Blood Flow -- 1.4.2 Link with Tracer-Perfusion Methods -- 1.5 Non-perfusion-Driven IVIM MRI -- 1.6 Conclusion -- Section II Other MRI Approaches toPerfusion Imaging -- Chapter 2. Other MRI Approaches to Perfusion Imaging (ASL, DSC, DCE) Emmanuel L. Barbier, Sylvie Grand, Alexandre Krainik, and Jan M. Warnking -- 2.1 The Perfusion Parameters: The Microvascular Network and Physiological Principles -- 2.2 Perfusion Tracers -- 2.3 Biophysical Modeling of Nondiffusible Tracers -- 2.3.1 Dynamic Approach -- 2.3.2 Steady-State Approach -- 2.4 Biophysical Modeling of Diffusible Tracers -- 2.5 Exogenous Tracers: DSC, Steady-State Approaches, and DCE -- 2.5.1 Impact of Exogenous Tracers on the MR Signal -- 2.5.2 Dynamic Susceptibility Contrast MRI -- 2.5.3 Steady-State Susceptibility MRI -- 2.5.4 Dynamic Contrast-Enhanced MRI -- 2.6 Endogenous Tracer: Arterial Spin Labeling -- 2.6.1 ASL MRI Sequences -- 2.6.2 Analyzing the ASL Signal -- 2.6.3 Applications of ASL -- 2.7 Conclusion -- Section III Clinical Applications of IVIM MRI Part 1: Neurological Applications -- Chapter 3. Clinical Applications of IVIM MRI to the Nervous System C. Federau 3.1 Introduction -- 3.2 Validations Studies of IVIM Perfusion Imaging in the Brain -- 3.3 Clinical Application of IVIM Perfusion Imaging in the Brain -- 3.3.1 Stroke -- 3.3.2 Cerebral Death -- 3.3.3 Detection of Vasospasms Related Perfusion Anomalies -- 3.3.4 Cerebral Small Vessel Disease -- 3.3.5 Neoangiogenesis in Brain Tumors -- 3.3.6 Detection of Perfusion Anomalies in the Papilla of the Optic Nerve -- Chapter 4. IVIM MRI: A Window to the Pathophysiology Underlying Cerebral Small Vessel Disease Jacobus F. A. Jansen, Sau May Wong, and Walter H. Backes -- 4.1 Cerebral Small Vessel Disease -- 4.2 Impairment of Cerebral Blood Flow -- 4.3 Intravoxel Incoherent Motion Imaging Metrics as a Marker of Pathophysiology -- 4.4 Applications of IVIM in cSVD -- 4.5 Discussion -- 4.6 Parenchymal Damage -- 4.7 On the Validity of IVIM Models -- 4.8 Clinical Implications -- 4.9 Conclusions -- Chapter 5. IVIM fMRI: Brain Activation with a High Spatial Specificity and Resolution Allen W. Song, Iain Bruce, Christopher Petty, and Nan-Kuei Chen -- 5.1 Introduction -- 5.2 IVIM fMRI Needs a High Spatial Resolution -- 5.3 IVIM fMRI during Motor Activation at a High Spatial Resolution -- 5.4 Discussions and Conclusions -- Section III Clinical Applications of IVIM MRI Part 2: Body IVIM MRI -- Chapter 6. IVIM in the Body: A General Overview Matthew R. Orton, Neil P. Jerome, Mihaela Rata, and Dow-Mu Koh -- 6.1 Introduction -- 6.2 Technical Considerations -- 6.2.1 Selection of b Values -- 6.2.2 Motion Control -- 6.2.3 Measurement Repeatability -- 6.3 Overview of the Clinical Applications of IVIM in the Body -- 6.3.1 Disease Detection -- 6.3.2 Lesion Characterization -- 6.3.3 Evaluation of Organ Function -- 6.3.4 Evaluation of Treatment Response -- 6.3.5 Clinical Challenges and Future Work -- Chapter 7. Head and Neck IVIM MRI Takashi Nakamura and Misa Sumi 7.1 Authentic and Geographic Estimations of Perfusion and Diffusion Properties for Head and Neck IVIM MRI -- 7.2 Head and Neck Squamous Cell Carcinomas -- 7.2.1 Perfusion and Diffusion Characteristics of Head and Neck Squamous Cell Carcinomas -- 7.2.2 Metastatic vs. Nonmetastatic Lymph Nodes in the Neck -- 7.2.3 Prediction of Treatment Response in Head and Neck Cancer -- 7.3 Lymphomas -- 7.3.1 Perfusion and Diffusion Characteristics of Nodal/Extranodal Lymphomas -- 7.3.2 Differential Diagnosis from Nasopharyngeal Cancer -- 7.4 Salivary Gland Tumors -- 7.4.1 Diffusion and Perfusion Characteristics of Salivary Gland Tumors -- 7.4.2 IVIM MRI-Based Differentiation of Benign and Malignant Salivary Gland Tumors -- 7.5 Masticator Muscles -- 7.5.1 Perfusion and Diffusion Kinetics of the Masticator Muscles during Clenching -- Chapter 8. IVIM MRI of the Breast Mami Iima and Masako Kataoka -- 8.1 Using IVIM to Distinguish Malignant from Benign Lesions and Normal Breast Tissue -- 8.2 IVIM for Identification of Prognostic Factors/Subtypes in Breast Cancers -- 8.3 The Multiparametric Approach: IVIM in Combination with Dynamic Contrast-Enhanced MRI, DWI, or Positron-Emission Tomography/mri -- 8.4 IVIM for Prediction of the Treatment Response -- 8.5 IVIM in Lactation -- 8.6 Optimal Fitting Method and Choice of b Values -- 8.6.1 Exhaustive (or Dictionary-based) Approach without Fitting -- 8.6.2 Simplified Approach without Fitting -- 8.7 Conclusions -- Chapter 9. Cardiac IVIM MRI Zhiyong Li and Anna Mou -- 9.1 Implementation of Cardiac IVIM -- 9.2 Choice of b Values -- 9.3 Assessment of IVIM Quality and Quantitative Analysis -- 9.3.1 Reproducibility of IVIM Parameters in Cardiac IVIM -- 9.3.2 Normal Values of CMR IVIM Parameters -- 9.4 Clinical Application of CMR IVIM -- Chapter 10. Liver Fibrosis Shintaro Ichikawa and Utaroh Motosugi -- 10.1 Introduction 10.2 Pathologic Features of Liver Fibrosis -- 10.3 ADC Value for Staging Liver Fibrosis -- 10.4 IVIM for Staging Liver Fibrosis -- 10.4.1 Diagnostic Performance of IVIM for Liver Fibrosis -- 10.4.2 Factors Influencing IVIM Values -- 10.4.3 Drawbacks of IVIM for Staging Liver Fibrosis -- 10.5 Conclusion -- Chapter 11. Assessment of Liver Tumors with IVIM Diffusion-Weighted Imaging Stefanie J. Hectors, Sara Lewis, and Bachir Taouli -- 11.1 Introduction -- 11.2 Background on Focal Liver Lesions -- 11.3 Current Evidence on the Use of DWI and ADC for Liver Tumor Detection and Characterization -- 11.3.1 DWI for Liver Lesion Detection -- 11.3.2 DWI for Lesion Characterization -- 11.4 IVIM DWI for the Assessment of Liver Lesions: Technical Considerations -- 11.4.1 Acquisition -- 11.4.2 Postprocessing -- 11.4.3 Quality Control -- 11.5 Applications of IVIM for the Assessment of FLL -- 11.5.1 Characterization of Benign and Malignant Liver Lesions -- 11.5.2 Potential Role of IVIM as a Surrogate Marker for Perfusion and Enhancement -- 11.5.3 Assessment of Post-Therapy Response -- 11.5.4 Summary -- 11.6 Limitations -- 11.7 Future Directions -- 11.8 Conclusions -- Chapter 12. IVIM MRI of the Pancreas Miriam Klauß, Philipp Mayer, and Bram Stieltjes -- 12.1 Introduction -- 12.2 Common Pancreatic Lesions -- 12.3 Pancreas IVIM Imaging/Acquisition Protocol -- 12.4 Pancreatic Adenocarcinoma -- 12.5 Differential Diagnosis between Pancreatic Cancer and Chronic Pancreatitis -- 12.6 PNETs -- 12.7 AIP/Therapy Monitoring -- 12.8 Pancreatic Fibrosis -- 12.9 Outlook/Perspective -- Chapter 13. IVIM MRI in the Kidney Moritz J. Schneider, Mike Notohamiprodjo, and Olaf Dietrich -- 13.1 Introduction -- 13.2 Data Acquisition and Processing -- 13.2.1 Pulse Sequence and Acquisition Parameters -- 13.2.2 Respiratory Motion -- 13.2.3 Data Analysis -- 13.3 Healthy Kidneys/Peculiarities 13.4 Applications in Diseased and Transplanted Kidneys -- 13.5 Conclusion: Open Questions and Future Directions -- Chapter 14. IVIM Diffusion Model in Prostate Cancer Baris Turkbey, Stephanie Harmon, Marcin Czarniecki, and Peter L. Choyke -- 14.1 Introduction -- 14.2 Prostate Cancer Detection Using the IVIM Model -- 14.3 Conclusion -- Chapter 15. Clinical Application of IVIM in the Female Pelvis Elaine Y. P. Lee and Pek-Lan Khong -- 15.1 Cervical Cancer -- 15.1.1 Tissue Differentiation -- 15.1.2 Relationship with Dynamic Contrast-Enhanced MRI -- 15.1.3 Tumor Differentiation -- 15.1.4 Treatment Response Assessment and Disease Prognostication -- 15.2 Technical Consideration -- 15.3 Other Applications of IVIM in the Female Pelvis -- 15.3.1 Malignant Diseases -- 15.3.2 Benign Disease -- 15.3.3 Treatment-Related Changes in the Pelvis -- 15.4 Roadmap to Clinical Translation -- 15.5 Conclusion -- Chapter 16. IVIM MRI of the Placenta Paddy J. Slator, Jana Hutter, Eleftheria Panagiotaki, Mary A. Rutherford, Joseph V. Hajnal, and -- 16.1 Introduction -- 16.1.1 Placental Markers of Pregnancy Complications -- 16.1.2 Imaging Markers of Pregnancy Complications -- 16.1.3 Challenges and Unique Potential of Placental MRI -- 16.1.4 Diffusion MRI of the Placenta -- 16.1.5 Placenta Structure -- 16.1.5.1 Movement of blood -- 16.1.5.2 Development across gestational age -- 16.1.5.3 How the placenta structure affects the dMRI signal -- 16.2 IVIM in the Placenta -- 16.2.1 Trends across the Gestational Age -- 16.2.2 Parameter Variation with Pathology -- 16.3 Anisotropic IVIM in the Placenta -- 16.3.1 dMRI Scans -- 16.3.2 Modeling -- 16.3.3 Results -- 16.3.4 Discussion -- 16.4 Discussion and Future Directions -- 16.4.1 Protocol Optimization -- 16.4.2 It's Not Just about the Placenta! -- 16.4.3 Joint Diffusion-Relaxometry -- 16.4.4 Histological Validation -- 16.5 Conclusion Chapter 17. Fetal IVIM MRI András Jakab, Raimund Kottke, Ianina Scheer, and Ruth Tuura |
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| Physical Description: | Online Resource |
| ISBN: | 9780429763496 |