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The Stent-Supported Percutaneous Angioplasty of the Carotid Artery vs. Endarterectomy

The Stent-Supported Percutaneous Angioplasty of the Carotid Artery versus Endarterectomy (SPACE) Trial is investigating if both treatment modalities are equivalent in the treatment of severe symptomatic carotid stenoses. Patients with symptomatic (transient ischaemic attack or minor stroke) stenosis...

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Bibliographic Details
Other Authors: Ringleb, Peter A. (Other) , Kunze, Albrecht (Other) , Allenberg, Jens-Rainer (Other) , Hennerici, Michael G. (Other) , Hacke, Werner (Other)
Format: Article (Journal)
Language:English
Published: June 1, 2004
In: Cerebrovascular diseases
Year: 2004, Volume: 18, Issue: 1, Pages: 66-68
ISSN:1421-9786
DOI:10.1159/000078752
Online Access:Resolving-System, Volltext: http://dx.doi.org/10.1159/000078752
Verlag, Volltext: http://www.karger.com/Article/Pdf/78752
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Author Notes:P.A. Ringleb, A. Kunze, J.R. Allenberg, M.G. Hennerici, O. Jansen, P.C. Maurer, H. Zeumer, W. Hacke
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Summary:The Stent-Supported Percutaneous Angioplasty of the Carotid Artery versus Endarterectomy (SPACE) Trial is investigating if both treatment modalities are equivalent in the treatment of severe symptomatic carotid stenoses. Patients with symptomatic (transient ischaemic attack or minor stroke) stenosis (above 50% following the North American Symptomatic Endarterectomy Trial criteria) eligible for both methods can be recruited into this trial. The primary endpoint is the incidence of an ipsilateral stroke or death between randomisation and day 30 after treatment. Surgeons as well as the interventionalists have to demonstrate their expertise prior to participation in the trial. Funding is mostly by public institutions (Federal Ministry of Education and Research and German Research Foundation). An external monitoring is applied. Thirty-two centres are currently taking part in the SPACE Trial that has been running in Germany, Austria and Switzerland for 3 years, and they have been able to recruit a total of around 670 patients. The definitive results of this study cannot be expected before 3-5 years.
Item Description:Gesehen am: 15.07.2015
Physical Description:Online Resource
ISSN:1421-9786
DOI:10.1159/000078752

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