Distinct roles for BAI1 and TIM-4 in the engulfment of dying neurons by microglia
The removal of dying neurons by microglia plays a key role in both vertebrate nervous system development and several diseases. Here, the authors use a quantitative live imaging approach to investigate neuronal-microglial interactions at single-cell resolution and establish the functions of the phosp...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
5 June 2014
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| In: |
Nature Communications
Year: 2014, Jahrgang: 5 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/ncomms5046 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1038/ncomms5046 Verlag, kostenfrei, Volltext: http://www.nature.com/ncomms/2014/140605/ncomms5046/full/ncomms5046.html 
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| Verfasserangaben: | Fargol Mazaheri, Oksana Breus, Sevi Durdu, Petra Haas, Jochen Wittbrodt, Darren Gilmour & Francesca Peri |
| Zusammenfassung: | The removal of dying neurons by microglia plays a key role in both vertebrate nervous system development and several diseases. Here, the authors use a quantitative live imaging approach to investigate neuronal-microglial interactions at single-cell resolution and establish the functions of the phosphatidylserine receptors, TIM-4 and BAI1, in neuronal engulfment. |
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| Beschreibung: | Gesehen am 08.02.2017 |
| Beschreibung: | Online Resource |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/ncomms5046 |