Hox genes: realising the importance of realisators

A recent study for the first time unravels a complete Hox regulatory network sufficient for the specification of a simple organ in Drosophila, linking Hox output to one specific group of executive genes, the realisators. As these genes have a direct effect on cellular functions and are required in m...

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Bibliographic Details
Main Author: Lohmann, Ingrid (Author)
Format: Article (Journal)
Language:English
Published: 5 December 2006
In: Current biology
Year: 2006, Volume: 16, Issue: 23, Pages: R988-R989
ISSN:1879-0445
DOI:10.1016/j.cub.2006.10.044
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1016/j.cub.2006.10.044
Verlag, kostenfrei, Volltext: http://www.sciencedirect.com/science/article/pii/S0960982206023827
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Author Notes:Ingrid Lohmann
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Summary:A recent study for the first time unravels a complete Hox regulatory network sufficient for the specification of a simple organ in Drosophila, linking Hox output to one specific group of executive genes, the realisators. As these genes have a direct effect on cellular functions and are required in most cell types, Hox genes may ultimately execute their function in controlling segmental fate by fine-tuning the spatial and temporal expression levels of these realisators.
Item Description:Gesehen am 08.05.2017
Physical Description:Online Resource
ISSN:1879-0445
DOI:10.1016/j.cub.2006.10.044