Hox genes: realising the importance of realisators
A recent study for the first time unravels a complete Hox regulatory network sufficient for the specification of a simple organ in Drosophila, linking Hox output to one specific group of executive genes, the realisators. As these genes have a direct effect on cellular functions and are required in m...
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| Main Author: | |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
5 December 2006
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| In: |
Current biology
Year: 2006, Volume: 16, Issue: 23, Pages: R988-R989 |
| ISSN: | 1879-0445 |
| DOI: | 10.1016/j.cub.2006.10.044 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1016/j.cub.2006.10.044 Verlag, kostenfrei, Volltext: http://www.sciencedirect.com/science/article/pii/S0960982206023827 |
| Author Notes: | Ingrid Lohmann |
| Summary: | A recent study for the first time unravels a complete Hox regulatory network sufficient for the specification of a simple organ in Drosophila, linking Hox output to one specific group of executive genes, the realisators. As these genes have a direct effect on cellular functions and are required in most cell types, Hox genes may ultimately execute their function in controlling segmental fate by fine-tuning the spatial and temporal expression levels of these realisators. |
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| Item Description: | Gesehen am 08.05.2017 |
| Physical Description: | Online Resource |
| ISSN: | 1879-0445 |
| DOI: | 10.1016/j.cub.2006.10.044 |