CENP-A confers a reduction in height on octameric nucleosomes
Nucleosomes with histone H3 replaced by CENP-A direct kinetochore assembly. CENP-A nucleosomes from human and Drosophila have been reported to have reduced heights as compared to canonical octameric H3 nucleosomes, thus suggesting a unique tetrameric hemisomal composition. We demonstrate that octame...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
5 May 2013
|
| In: |
Nature structural & molecular biology
Year: 2013, Volume: 20, Issue: 6, Pages: 763-765 |
| ISSN: | 1545-9985 |
| DOI: | 10.1038/nsmb.2574 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1038/nsmb.2574 Verlag, Volltext: https://www.nature.com/nsmb/journal/v20/n6/full/nsmb.2574.html#affil-auth 
|
| Author Notes: | Matthew D. D. Miell, Colin J. Fuller, Annika Guse, Helena M. Barysz, Andrew Downes, Tom Owen-Hughes, Juri Rappsilber, Aaron F. Straight & Robin C. Allshire |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 155839625X | ||
| 003 | DE-627 | ||
| 005 | 20220813170028.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 170510s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/nsmb.2574 |2 doi | |
| 035 | |a (DE-627)155839625X | ||
| 035 | |a (DE-576)488396255 | ||
| 035 | |a (DE-599)BSZ488396255 | ||
| 035 | |a (OCoLC)1340974554 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Miell, Matthew |e VerfasserIn |0 (DE-588)113173176X |0 (DE-627)886402875 |0 (DE-576)488396182 |4 aut | |
| 245 | 1 | 0 | |a CENP-A confers a reduction in height on octameric nucleosomes |c Matthew D. D. Miell, Colin J. Fuller, Annika Guse, Helena M. Barysz, Andrew Downes, Tom Owen-Hughes, Juri Rappsilber, Aaron F. Straight & Robin C. Allshire |
| 264 | 1 | |c 5 May 2013 | |
| 300 | |a 3 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 10.05.2017 | ||
| 520 | |a Nucleosomes with histone H3 replaced by CENP-A direct kinetochore assembly. CENP-A nucleosomes from human and Drosophila have been reported to have reduced heights as compared to canonical octameric H3 nucleosomes, thus suggesting a unique tetrameric hemisomal composition. We demonstrate that octameric CENP-A nucleosomes assembled in vitro exhibit reduced heights, indicating that they are physically distinct from H3 nucleosomes and negating the need to invoke the presence of hemisomes. | ||
| 650 | 4 | |a Histone variants | |
| 650 | 4 | |a Nucleosomes | |
| 700 | 1 | |a Guse, Annika |e VerfasserIn |0 (DE-588)1079253254 |0 (DE-627)840692730 |0 (DE-576)452309247 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature structural & molecular biology |d London [u.a.] : Nature Publishing Group, 2004 |g 20(2013), 6, Seite 763-765 |h Online-Ressource |w (DE-627)37683126X |w (DE-600)2131437-8 |w (DE-576)109293967 |x 1545-9985 |7 nnas |a CENP-A confers a reduction in height on octameric nucleosomes |
| 773 | 1 | 8 | |g volume:20 |g year:2013 |g number:6 |g pages:763-765 |g extent:3 |a CENP-A confers a reduction in height on octameric nucleosomes |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1038/nsmb.2574 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/nsmb/journal/v20/n6/full/nsmb.2574.html#affil-auth |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20170510 | ||
| 993 | |a Article | ||
| 994 | |a 2013 | ||
| 998 | |g 1079253254 |a Guse, Annika |m 1079253254:Guse, Annika |d 700000 |d 721000 |e 700000PG1079253254 |e 721000PG1079253254 |k 0/700000/ |k 1/700000/721000/ |p 3 | ||
| 999 | |a KXP-PPN155839625X |e 2969062534 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"id":{"zdb":["2131437-8"],"eki":["37683126X"],"issn":["1545-9985"]},"origin":[{"publisherPlace":"London [u.a.]","dateIssuedKey":"2004","publisher":"Nature Publishing Group","dateIssuedDisp":"2004-"}],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title":"Nature structural & molecular biology","title_sort":"Nature structural & molecular biology"}],"recId":"37683126X","language":["eng"],"note":["Gesehen am 01.03.05"],"disp":"CENP-A confers a reduction in height on octameric nucleosomesNature structural & molecular biology","type":{"media":"Online-Ressource","bibl":"periodical"},"part":{"pages":"763-765","issue":"6","year":"2013","extent":"3","text":"20(2013), 6, Seite 763-765","volume":"20"},"pubHistory":["11.2004 -"]}],"physDesc":[{"extent":"3 S."}],"id":{"doi":["10.1038/nsmb.2574"],"eki":["155839625X"]},"origin":[{"dateIssuedKey":"2013","dateIssuedDisp":"5 May 2013"}],"name":{"displayForm":["Matthew D. D. Miell, Colin J. Fuller, Annika Guse, Helena M. Barysz, Andrew Downes, Tom Owen-Hughes, Juri Rappsilber, Aaron F. Straight & Robin C. Allshire"]},"language":["eng"],"recId":"155839625X","type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 10.05.2017"],"title":[{"title":"CENP-A confers a reduction in height on octameric nucleosomes","title_sort":"CENP-A confers a reduction in height on octameric nucleosomes"}],"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Miell, Matthew","given":"Matthew","family":"Miell"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Guse, Annika","given":"Annika","family":"Guse"}]} | ||
| SRT | |a MIELLMATTHCENPACONFE5201 | ||