The V-ATPase: small cargo, large effects

About 30 years ago seminal reports of anion-sensitive proton-pumping activity associated with microsomal membranes initiated research on the plant vacuolar-type H+-ATPase (V-ATPase, VHA). Since, it has been firmly established that these complex molecular machines are essential for what can be define...

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Bibliographic Details
Main Authors: Schumacher, Karin (Author) , Krebs, Melanie (Author)
Format: Article (Journal)
Language:English
Published: 26th August 2010
In: Current opinion in plant biology
Year: 2010, Volume: 13, Issue: 6, Pages: 724-730
ISSN:1879-0356
DOI:10.1016/j.pbi.2010.07.003
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.pbi.2010.07.003
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1369526610001007
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Author Notes:Karin Schumacher, Melanie Krebs
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Summary:About 30 years ago seminal reports of anion-sensitive proton-pumping activity associated with microsomal membranes initiated research on the plant vacuolar-type H+-ATPase (V-ATPase, VHA). Since, it has been firmly established that these complex molecular machines are essential for what can be defined as cellular logistics. In a eukaryotic cell, the flow of goods between compartments is achieved either by protein-mediated membrane transport or via vesicular trafficking. Over the past years, it has become increasingly clear that V-ATPases do not only energize secondary active transport but are also important regulators of membrane trafficking.
Item Description:Gesehen am 10.05.2017
Physical Description:Online Resource
ISSN:1879-0356
DOI:10.1016/j.pbi.2010.07.003