The V-ATPase: small cargo, large effects
About 30 years ago seminal reports of anion-sensitive proton-pumping activity associated with microsomal membranes initiated research on the plant vacuolar-type H+-ATPase (V-ATPase, VHA). Since, it has been firmly established that these complex molecular machines are essential for what can be define...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
26th August 2010
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| In: |
Current opinion in plant biology
Year: 2010, Jahrgang: 13, Heft: 6, Pages: 724-730 |
| ISSN: | 1879-0356 |
| DOI: | 10.1016/j.pbi.2010.07.003 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.pbi.2010.07.003 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1369526610001007 
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| Verfasserangaben: | Karin Schumacher, Melanie Krebs |
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| 520 | |a About 30 years ago seminal reports of anion-sensitive proton-pumping activity associated with microsomal membranes initiated research on the plant vacuolar-type H+-ATPase (V-ATPase, VHA). Since, it has been firmly established that these complex molecular machines are essential for what can be defined as cellular logistics. In a eukaryotic cell, the flow of goods between compartments is achieved either by protein-mediated membrane transport or via vesicular trafficking. Over the past years, it has become increasingly clear that V-ATPases do not only energize secondary active transport but are also important regulators of membrane trafficking. | ||
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