Curvature recognition and force generation in phagocytosis
The uptake of particles by actin-powered invagination of the plasma membrane is common to protozoa and to phagocytes involved in the immune response of higher organisms. The question addressed here is how a phagocyte may use geometric cues to optimize force generation for the uptake of a particle. W...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
29 December 2010
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| In: |
BMC biology
Year: 2010, Jahrgang: 8 |
| ISSN: | 1741-7007 |
| DOI: | 10.1186/1741-7007-8-154 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/1741-7007-8-154
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| Verfasserangaben: | Margaret Clarke, Ulrike Engel, Jennifer Giorgione, Annette Müller-Taubenberger, Jana Prassler, Douwe Veltman, Günther Gerisch |
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| 520 | |a The uptake of particles by actin-powered invagination of the plasma membrane is common to protozoa and to phagocytes involved in the immune response of higher organisms. The question addressed here is how a phagocyte may use geometric cues to optimize force generation for the uptake of a particle. We survey mechanisms that enable a phagocyte to remodel actin organization in response to particles of complex shape. | ||
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