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MTHFD1 controls DNA methylation in Arabidopsis

DNA methylation contributes to transcriptional silencing. Here, Groth et al.show that mutant plants defective in MTHFD1, an enzyme involved in folate metabolism, have a DNA hypomethylation phenotype highlighting the link between one-carbon metabolism and DNA methylation, which is mediated by SAM as...

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Bibliographic Details
Main Authors: Groth, Martin (Author) , Wirtz, Markus (Author) , Hell, Rüdiger (Author)
Format: Article (Journal)
Language:English
Published: 13 June 2016
In: Nature Communications
Year: 2016, Volume: 7
ISSN:2041-1723
DOI:10.1038/ncomms11640
Online Access:Verlag, Volltext: http://dx.doi.org/10.1038/ncomms11640
Verlag, Volltext: http://www.nature.com/ncomms/2016/160613/ncomms11640/full/ncomms11640.html
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Author Notes:Martin Groth, Guillaume Moissiard, Markus Wirtz, Haifeng Wang, Carolina Garcia-Salinas, Perla A. Ramos-Parra, Sylvain Bischof, Suhua Feng, Shawn J. Cokus, Amala John, Danielle C. Smith, Jixian Zhai, Christopher J. Hale, Jeff A. Long, Ruediger Hell, Rocío I. Díaz de la Garza & Steven E. Jacobsen

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