Nocturnal sleep duration and cognitive impairment in a population-based study of older adults
Objective: We aimed to investigate the association between nocturnal sleep duration, changes in nocturnal sleep duration and cognitive impairment in older adults. Methods: 4010 participants of a population-based cohort study provided information on nocturnal sleep duration at baseline (1991-1995) an...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2010
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| In: |
International journal of geriatric psychiatry
Year: 2010, Volume: 25, Issue: 1, Pages: 100-109 |
| ISSN: | 1099-1166 |
| DOI: | 10.1002/gps.2305 |
| Online Access: | Verlag, Pay-per-use, Volltext: http://dx.doi.org/10.1002/gps.2305 Verlag, Pay-per-use, Volltext: http://onlinelibrary.wiley.com/doi/10.1002/gps.2305/abstract 
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| Author Notes: | Adrian Loerbroks, Desiree Debling, Manfred Amelang and Til Stürmer |
| Summary: | Objective: We aimed to investigate the association between nocturnal sleep duration, changes in nocturnal sleep duration and cognitive impairment in older adults. Methods: 4010 participants of a population-based cohort study provided information on nocturnal sleep duration at baseline (1991-1995) and at follow-up (2002/2003). 792 follow-up participants aged 70+ by 2006 participated in telephone-based cognitive assessments. Several cognitive tests were used including the telephone interview for cognitive status (TICS). Cognitive impairment was defined as <31 points on the TICS (13.0%) and as below this percentile on the other tests. Based on individual tests, a verbal memory score and a total score were constructed. Multivariable prevalence ratios (PRs) of cognitive impairment and 95% confidence intervals (95%CIs) were computed using Poisson regression. Analyses were restricted to those free of depression in 2002/2003 (n = 695). Results: Sleeping ≤6 or 8 h per night (versus 7 h) were unrelated to cognitive impairment. Sleeping ≥9 h was positively, although imprecisely, associated with impairment of verbal memory (PR = 1.7, 95%CI = 1.0, 3.0), and less pronounced with the other cognitive measures. An increase in sleep duration from 7-8 h in 1992-1995 to ≥9 h 8.5 years later (versus sleeping 7-8 h at both time points) was associated with an increased prevalence of cognitive impairment according to the TICS (PR = 2.1, 95% = 1.0, 4.5) and the verbal memory score (PR = 2.0, 95%CI = 1.0, 3.8). Conclusions: Increases in sleep duration are associated with cognitive impairment. A biological explanation for this association is currently lacking. Increases in sleep duration could be a marker of cognitive deficits. Copyright © 2009 John Wiley & Sons, Ltd. |
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| Item Description: | Gesehen am 20.06.2017 Article was first published on 22 June 2009 |
| Physical Description: | Online Resource |
| ISSN: | 1099-1166 |
| DOI: | 10.1002/gps.2305 |