Point of care coagulation testing in neurosurgery
Impaired haemostasis represents a major risk factor for bleeding complications in neurosurgical patients. Coagulopathy commonly occurs after (brain) trauma and major haemorrhage or originates from antithrombotic medication. Point of care (POC) devices for bedside assessment of haemostatic parameters...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2015
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| In: |
Journal of clinical neuroscience
Year: 2014, Volume: 22, Issue: 2, Pages: 252-257 |
| ISSN: | 1532-2653 |
| DOI: | 10.1016/j.jocn.2014.07.029 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.jocn.2014.07.029 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0967586814005578 
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| Author Notes: | Christopher Beynon, Andreas W. Unterberg, Oliver W. Sakowitz |
| Summary: | Impaired haemostasis represents a major risk factor for bleeding complications in neurosurgical patients. Coagulopathy commonly occurs after (brain) trauma and major haemorrhage or originates from antithrombotic medication. Point of care (POC) devices for bedside assessment of haemostatic parameters are increasingly used in various medical specialties. Results can be instantly implemented into treatment modalities as results are delivered within a very short period. POC coagulation testing has also shown beneficial effects in the treatment of neurosurgical patients. Identification of hyperfibrinolysis is achieved through viscoelastic testing of haemostasis and bedside coagulometry hastens the management of anticoagulated patients in need of urgent neurosurgical procedures. Results of POC testing of platelet function have been correlated with patient outcomes after traumatic brain injury and furthermore, quantification of antiplatelet medication effects on platelet activity is made possible through the use of these devices. Further studies are needed to characterise the potential of POC testing of platelet function. Antiplatelet medication plays an important role in regard to haemorrhagic and thromboembolic risks. Therefore, POC testing of platelet activity may improve treatment modalities in patients undergoing neurosurgical procedures as well as neurointerventional procedures (such as intracranial stent placement). In this article we summarise the available data of POC testing in neurosurgical patients and discuss the potential of these devices in this field. POC technologies have improved patient care in various medical fields and in our view it is likely that this will also apply to the field of neurosurgery. |
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| Item Description: | Published online: 28 July 2014 Gesehen am 21.06.2017 |
| Physical Description: | Online Resource |
| ISSN: | 1532-2653 |
| DOI: | 10.1016/j.jocn.2014.07.029 |